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Lrrc63 Gene Detail
Summary
  • Symbol
    Lrrc63
  • Name
    leucine rich repeat containing 63
  • Synonyms
    4921509B22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918109
    NCBI Gene: 70859
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:75321743-75368321 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 39.59 cM, cytoband D2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1219 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918109
 protein coding gene Chr14:75321743-75368402 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021566
 protein coding gene Chr14:69888213-69938772 (-)
A/J MGP_AJ_G0021524
 protein coding gene Chr14:68334886-68381964 (-)
AKR/J MGP_AKRJ_G0021501
 protein coding gene Chr14:70355058-70411128 (-)
BALB/cJ MGP_BALBcJ_G0021531
 protein coding gene Chr14:68133435-68184300 (-)
C3H/HeJ MGP_C3HHeJ_G0021308
 protein coding gene Chr14:70093825-70140516 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021971
 protein coding gene Chr14:72961253-73012594 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019509
 protein coding gene Chr14:65983013-66027243 (-)
CAST/EiJ MGP_CASTEiJ_G0020825
 protein coding gene Chr14:66756350-66808005 (-)
CBA/J MGP_CBAJ_G0021276
 protein coding gene Chr14:75296537-75344809 (-)
DBA/2J MGP_DBA2J_G0021399
 protein coding gene Chr14:67742864-67790519 (-)
FVB/NJ MGP_FVBNJ_G0021377
 protein coding gene Chr14:67071302-67119989 (-)
LP/J MGP_LPJ_G0021469
 protein coding gene Chr14:71048037-71100516 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021404
 protein coding gene Chr14:74069098-74123494 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021994
 protein coding gene Chr14:69651138-69702405 (-)
PWK/PhJ MGP_PWKPhJ_G0020568
 protein coding gene Chr14:64477636-64524430 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020404
 protein coding gene Chr14:65600954-65646835 (-)
WSB/EiJ MGP_WSBEiJ_G0020878
 protein coding gene Chr14:69986387-70033516 (-)



Homology
more
  • Human Ortholog
    LRRC63, leucine rich repeat containing 63
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC63, leucine rich repeat containing 63
  • Links
    NCBI Gene ID: 220416
    UniProt: Q05C16

  • Chr Location
    13q14.13; chr13:46211928-46277115 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000021997 Ensembl Gene Model | MGI Sequence Detail 46579 C57BL/6J ±  kb
    transcript ENSMUST00000022574 Ensembl | MGI Sequence Detail 2517 Not Applicable  
    polypeptide ENSMUSP00000022574 Ensembl | MGI Sequence Detail 638 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      Genomic 2
      cDNA 6

      Microarray probesets 2
    References
    more
    • Summaries
      All 27
      Gene Ontology 1
      Phenotypes 7
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory