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Prss22 Gene Detail
Summary
  • Symbol
    Prss22
  • Name
    serine protease 22
  • Synonyms
    4733401N09Rik, BSSP-4, SP001LA
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918085
    NCBI Gene: 70835
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:24212508-24217074 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 12.18 cM, cytoband A3.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    204 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918085
 protein coding gene Chr17:24212508-24219696 (-)
129S1/SvImJ ENSMUSG00200037822
 protein coding gene Chr17:19646251-19650833 (-)
A/J ENSMUSG00195052300
 protein coding gene Chr17:20665033-20669613 (-)
AKR/J ENSMUSG00220026206
 protein coding gene Chr17:19712872-19722638 (-)
BALB/cJ ENSMUSG00180014508
 protein coding gene Chr17:19947988-19952567 (-)
C3H/HeJ ENSMUSG00175038897
 protein coding gene Chr17:19701955-19706564 (-)
C57BL/6NJ ENSMUSG00215041244
 protein coding gene Chr17:19720302-19724870 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021170
 protein coding gene Chr17:19803663-19808275 (-)
CAST/EiJ ENSTCUG00005044560
 protein coding gene Chr17:20292093-20296680 (-)
CBA/J ENSMUSG00210029059
 protein coding gene Chr17:19540793-19545404 (-)
DBA/2J ENSMUSG00185052327
 protein coding gene Chr17:21753424-21758002 (-)
FVB/NJ ENSMUSG00205028354
 protein coding gene Chr17:20009226-20013843 (-)
JF1/MsJ ENSUMUG00000056840
 protein coding gene Chr17:21212120-21216686 (-)
LP/J ENSMUSG00230055017
 protein coding gene Chr17:23151261-23155566 (-)
NOD/ShiLtJ ENSMUSG00190022934
 protein coding gene Chr17:19642142-19646722 (-)
NZO/HlLtJ ENSMUSG00225049346
 protein coding gene Chr17:25072883-25077188 (-)
PWK/PhJ ENSLUMG00010017566
 protein coding gene Chr17:19121166-19125760 (-)
SPRET/EiJ ENSMSPG00010036025
 protein coding gene Chr17:20455232-20459856 (-)
WSB/EiJ ENSIUOG00005050718
 protein coding gene Chr17:20400607-20405227 (-)



Homology
more
  • Human Ortholog
    PRSS22, serine protease 22
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRSS22, serine protease 22
  • Synonyms
    BSSP-4, hBSSP-4, SP001LA, TPSE1
  • Links
    NCBI Gene ID: 64063
    UniProt: Q9GZN4

  • Chr Location
    16p13.3; chr16:2852728-2858210 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    619
  • Tissues
    21
  • cDNA Data
    5
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045027 Ensembl Gene Model | MGI Sequence Detail 4567 C57BL/6J ±  kb
transcript ENSMUST00000041649 Ensembl | MGI Sequence Detail 1324 Not Applicable  
polypeptide ENSMUSP00000039808 Ensembl | MGI Sequence Detail 307 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 5
    Primer pair 2

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:277331 Sah RK, et al., Transcriptome profiling of mouse brain and lung under Dip2a regulation using RNA-sequencing. PLoS One. 2019;14(7):e0213702
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory