Utp20 MGI Mouse Gene Detail - MGI:1917933 - UTP20 small subunit processome component

Symbol

Utp20
Name

UTP20 small subunit processome component
Synonyms

3830408P06Rik, DRIM, mDRIM

Feature Type

protein coding gene
IDs

MGI:1917933
NCBI Gene: 70683
Alliance

gene page
Transcription Start Sites

7 TSS

Sequence Map

Chr10:88582469-88662666 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 10, 44.21 cM
Mapping Data

2 experiments

SNPs within 2kb

393 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1917933	protein coding gene	Chr10:88582469-88662676 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0017632	protein coding gene	Chr10:89872756-89959292 (-)
A/J	MGP_AJ_G0017611	protein coding gene	Chr10:86816935-86896561 (-)
AKR/J	MGP_AKRJ_G0017569	protein coding gene	Chr10:89294308-89377196 (-)
BALB/cJ	MGP_BALBcJ_G0017574	protein coding gene	Chr10:87092086-87171397 (-)
C3H/HeJ	MGP_C3HHeJ_G0017397	protein coding gene	Chr10:89285810-89372436 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0018031	protein coding gene	Chr10:92875554-92958371 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0015713	protein coding gene	Chr10:82570526-82651595 (-)
CAST/EiJ	MGP_CASTEiJ_G0016962	protein coding gene	Chr10:89199241-89278281 (-)
CBA/J	MGP_CBAJ_G0017366	protein coding gene	Chr10:96732193-96819443 (-)
DBA/2J	MGP_DBA2J_G0017472	protein coding gene	Chr10:85961155-86043400 (-)
FVB/NJ	MGP_FVBNJ_G0017464	protein coding gene	Chr10:85164863-85244310 (-)
LP/J	MGP_LPJ_G0017546	protein coding gene	Chr10:90540221-90620511 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0017495	protein coding gene	Chr10:98219177-98300399 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0018068	protein coding gene	Chr10:89137835-89230625 (-)
PWK/PhJ	MGP_PWKPhJ_G0016743	protein coding gene	Chr10:85958271-86041785 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0016531	protein coding gene	Chr10:87880287-87975816 (-)
WSB/EiJ	MGP_WSBEiJ_G0017021	protein coding gene	Chr10:89128878-89210412 (-)

Human Ortholog

UTP20, UTP20 small subunit processome component

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

UTP20, UTP20 small subunit processome component
Synonyms

1A6/DRIM, DRIM
Links

HGNC:17897

NCBI Gene ID: 27340

neXtProt AC: NX_O75691

UniProt: O75691
Chr Location

12q23.2; chr12:101280105-101386618 (+) GRCh38

MGI Vertebrate Homology

Utp20 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: UTP20
Gene Tree

Utp20

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Phenotype Summary

5 phenotypes from 1 allele in 1 genetic background
12 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

14
Chemically induced (other)

1
Endonuclease-mediated

1
Gene trapped

11
Transposon induced

1
Genomic Mutations

2 involving Utp20
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

137 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

12
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

718
Tissues

6
cDNA Data

156
Literature Summary

3

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase utp20

ZFIN utp20

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All Sequences

50
RefSeq

2
UniProt

6
CCDS

CCDS48667.1

Ensembl

ENSMUSG00000004356 (Evidence)
NCBI Gene

70683

			Length	Strain/Species	Flank
genomic	ENSMUSG00000004356	Ensembl Gene Model \| MGI Sequence Detail	80198	C57BL/6J	± kb
transcript	ENSMUST00000004470	Ensembl \| MGI Sequence Detail	8821	Not Applicable
polypeptide	ENSMUSP00000004470	Ensembl \| MGI Sequence Detail	2789	Not Applicable

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UniProt

6 Sequences
Protein Ontology

PR:000017205 small subunit processome component 20

(term hierarchy)
InterPro Domains

IPR011989 Armadillo-like helical

IPR016024 Armadillo-type fold

IPR046523 U3 small nucleolar RNA-associated protein 20, C-terminal

IPR011430 U3 small nucleolar RNA-associated protein 20, N-terminal

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All nucleic 158

cDNA 157

Primer pair 1

Microarray probesets 3

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MGI:2143504

Summaries

All 39

Developmental Gene Expression 3

Gene Ontology 3

Phenotypes 12
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:284490 Varum S, et al., Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation. Cell Stem Cell. 2019 Apr 4;24(4):637-653.e9

TSS for Utp20:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr98858	Chr10:88662634-88662699 (-)	-1 bp
Tssr98857	Chr10:88662599-88662604 (-)	64 bp
Tssr98856	Chr10:88662571-88662580 (-)	90 bp
Tssr98855	Chr10:88624243-88624250 (-)	38,419 bp
Tssr98854	Chr10:88601444-88601460 (-)	61,214 bp
Tssr98853	Chr10:88601351-88601354 (-)	61,313 bp
Tssr98852	Chr10:88587155-88587159 (-)	75,509 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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