Tmem144 MGI Mouse Gene Detail - MGI:1917902

Symbol

Tmem144
Name

transmembrane protein 144
Synonyms

1110057I03Rik, 5730537D05Rik

Feature Type

protein coding gene
IDs

MGI:1917902
NCBI Gene: 70652
Alliance

gene page
Transcription Start Sites

10 TSS

Sequence Map

Chr3:79719871-79760080 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 35.07 cM, cytoband F1
Mapping Data

3 experiments

SNPs within 2kb

3055 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1917902	protein coding gene	Chr3:79719871-79760093 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0027317	protein coding gene	Chr3:79518987-79563550 (-)
A/J	MGP_AJ_G0027279	protein coding gene	Chr3:76916500-76955655 (-)
AKR/J	MGP_AKRJ_G0027247	protein coding gene	Chr3:78685986-78725679 (-)
BALB/cJ	MGP_BALBcJ_G0027290	protein coding gene	Chr3:76951638-76992099 (-)
C3H/HeJ	MGP_C3HHeJ_G0027034	protein coding gene	Chr3:79018682-79062243 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0027736	protein coding gene	Chr3:82566340-82607579 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025089	protein coding gene	Chr3:72843112-72883705 (-)
CAST/EiJ	MGP_CASTEiJ_G0026481	protein coding gene	Chr3:79088822-79126341 (-)
CBA/J	MGP_CBAJ_G0027009	protein coding gene	Chr3:85283387-85325879 (-)
DBA/2J	MGP_DBA2J_G0027145	protein coding gene	Chr3:76483385-76522760 (-)
FVB/NJ	MGP_FVBNJ_G0027113	protein coding gene	Chr3:74813518-74853674 (-)
LP/J	MGP_LPJ_G0027253	protein coding gene	Chr3:80489720-80529572 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027132	protein coding gene	Chr3:91538945-91581565 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0027794	protein coding gene	Chr3:78526801-78567799 (-)
PWK/PhJ	MGP_PWKPhJ_G0026215	protein coding gene	Chr3:76230646-76274580 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0026031	protein coding gene	Chr3:77677483-77719761 (-)
WSB/EiJ	MGP_WSBEiJ_G0026559	protein coding gene	Chr3:78866240-78907862 (-)

Human Ortholog

TMEM144, transmembrane protein 144

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TMEM144, transmembrane protein 144
Synonyms

SLC35G7
Links

HGNC:25633

NCBI Gene ID: 55314

UniProt: Q7Z5S9
Chr Location

4q32.1; chr4:158201604-158255416 (+) GRCh38

MGI Vertebrate Homology

Tmem144 stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: TMEM144
Gene Tree

Tmem144

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References

1 with disease annotations

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Phenotype Summary

11 phenotype references

All Mutations and Alleles

8
Chemically induced (other)

1
Endonuclease-mediated

4
Radiation induced

1
Targeted

2
Genomic Mutations

2 involving Tmem144
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

32 strains or lines available

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Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

5

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase tmem144

ZFIN tmem144b

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All Sequences

65
RefSeq

25
UniProt

3
CCDS

CCDS17421.1

Ensembl

ENSMUSG00000027956 (Evidence)
NCBI Gene

70652

			Length	Strain/Species	Flank
genomic	ENSMUSG00000027956	Ensembl Gene Model \| MGI Sequence Detail	40210	C57BL/6J	± kb
transcript	ENSMUST00000029568	Ensembl \| MGI Sequence Detail	2898	Not Applicable
polypeptide	ENSMUSP00000029568	Ensembl \| MGI Sequence Detail	348	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000032281 transmembrane protein 144

(term hierarchy)
InterPro Domains

IPR010651 Sugar transport protein

IPR012435 TMEM144

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All nucleic 5

cDNA 5

Microarray probesets 3

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MGI:1916079

Summaries

All 29

Diseases 1

Phenotypes 11
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Tmem144:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr33751	Chr3:79760067-79760091 (-)	1 bp
Tssr33750	Chr3:79750743-79750749 (-)	9,334 bp
Tssr33749	Chr3:79750164-79750239 (-)	9,878 bp
Tssr33748	Chr3:79749949-79749991 (-)	10,110 bp
Tssr33747	Chr3:79732895-79732908 (-)	27,178 bp
Tssr33746	Chr3:79732869-79732879 (-)	27,206 bp
Tssr33745	Chr3:79732844-79732866 (-)	27,225 bp
Tssr33744	Chr3:79732826-79732843 (-)	27,245 bp
Tssr33743	Chr3:79732799-79732813 (-)	27,274 bp
Tssr33742	Chr3:79732772-79732785 (-)	27,301 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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