About   Help   FAQ
Btbd7 Gene Detail
Summary
  • Symbol
    Btbd7
  • Name
    BTB domain containing 7
  • Synonyms
    5730507E09Rik, E130118E17Rik, FUP1, mKIAA1525
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917858
    NCBI Gene: 238386
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:102747056-102844730 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 52.25 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3368 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917858
 protein coding gene Chr12:102747056-102844733 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020041
 protein coding gene Chr12:104443208-104531397 (-)
A/J MGP_AJ_G0019997
 protein coding gene Chr12:100424037-100515627 (-)
AKR/J MGP_AKRJ_G0019973
 protein coding gene Chr12:103266725-103351274 (-)
BALB/cJ MGP_BALBcJ_G0019983
 protein coding gene Chr12:100777162-100869114 (-)
C3H/HeJ MGP_C3HHeJ_G0019785
 protein coding gene Chr12:103740140-103832659 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020432
 protein coding gene Chr12:107683385-107784938 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018045
 protein coding gene Chr12:97475830-97556554 (-)
CAST/EiJ MGP_CASTEiJ_G0019331
 protein coding gene Chr12:98586689-98678140 (-)
CBA/J MGP_CBAJ_G0019757
 protein coding gene Chr12:111685698-111786109 (-)
DBA/2J MGP_DBA2J_G0019868
 protein coding gene Chr12:99944092-100032862 (-)
FVB/NJ MGP_FVBNJ_G0019857
 protein coding gene Chr12:98674051-98769460 (-)
LP/J MGP_LPJ_G0019944
 protein coding gene Chr12:104283718-104377266 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019897
 protein coding gene Chr12:115145923-115250460 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020461
 protein coding gene Chr12:102791461-102883715 (-)
PWK/PhJ MGP_PWKPhJ_G0019094
 protein coding gene Chr12:94501062-94591529 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018890
 protein coding gene Chr12:96979404-97068502 (-)
WSB/EiJ MGP_WSBEiJ_G0019385
 protein coding gene Chr12:103675145-103770689 (-)



Homology
more
  • Human Ortholog
    BTBD7, BTB domain containing 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BTBD7, BTB domain containing 7
  • Synonyms
    FUP1
  • Links
    NCBI Gene ID: 55727
    UniProt: Q9P203

  • Chr Location
    14q32.12; chr14:93237550-93333092 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotypes from 2 alleles in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display fetal and postnatal lethality, impaired branching morphogenesis in the submandibular salivary gland, lung and kidney, and impaired migration of submandibular gland outer bud cells.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    771
  • Tissues
    44
  • cDNA Data
    13
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000041702 Ensembl Gene Model | MGI Sequence Detail 97675 C57BL/6J ±  kb
    transcript ENSMUST00000223554 Ensembl | MGI Sequence Detail 8157 Not Applicable  
    polypeptide ENSMUSP00000152426 Ensembl | MGI Sequence Detail 1130 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 13
      Primer pair 1

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:2443368
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 6
      Gene Ontology 2
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory