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Adamdec1 Gene Detail
Summary
  • Symbol
    Adamdec1
  • Name
    ADAM-like, decysin 1
  • Synonyms
    2210414L24Rik, Dcsn
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917650
    NCBI Gene: 58860
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:68800836-68819521 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 35.69 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    279 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917650
 protein coding gene Chr14:68800829-68819544 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021511
 protein coding gene Chr14:63334124-63352779 (-)
A/J MGP_AJ_G0021470
 protein coding gene Chr14:61813802-61832494 (-)
AKR/J MGP_AKRJ_G0021446
 protein coding gene Chr14:63903316-63922012 (-)
BALB/cJ MGP_BALBcJ_G0021476
 protein coding gene Chr14:61797851-61817261 (-)
C3H/HeJ MGP_C3HHeJ_G0021253
 protein coding gene Chr14:63642642-63661301 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021915
 protein coding gene Chr14:66201284-66224204 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019455
 protein coding gene Chr14:59695328-59714134 (-)
CAST/EiJ MGP_CASTEiJ_G0020770
 protein coding gene Chr14:60155143-60175876 (-)
CBA/J MGP_CBAJ_G0021220
 protein coding gene Chr14:68221274-68241669 (-)
DBA/2J MGP_DBA2J_G0021343
 protein coding gene Chr14:61430571-61449607 (-)
FVB/NJ MGP_FVBNJ_G0021322
 protein coding gene Chr14:60840347-60858833 (-)
LP/J MGP_LPJ_G0021418
 protein coding gene Chr14:64395350-64414001 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021351
 protein coding gene Chr14:67193238-67217288 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021938
 protein coding gene Chr14:63143897-63164081 (-)
PWK/PhJ MGP_PWKPhJ_G0020514
 protein coding gene Chr14:58185052-58203792 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020347
 protein coding gene Chr14:59078920-59097652 (-)
WSB/EiJ MGP_WSBEiJ_G0020823
 protein coding gene Chr14:63463263-63481834 (-)



Homology
more
  • Human Ortholog
    ADAMDEC1, ADAM like decysin 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ADAMDEC1, ADAM like decysin 1
  • Synonyms
    M12.219
  • Links
    NCBI Gene ID: 27299
    neXtProt AC: NX_O15204
    UniProt: O15204

  • Chr Location
    8p21.2; chr8:24384285-24406013 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele are more susceptible to the induction of bacterial and chemical induced colitis, showing more weight loss, increased mortality, increased neutrophil infiltration and greater IL-6 and Il-1beta secretion.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    734
  • Tissues
    4
  • cDNA Data
    30
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 58860 NCBI Gene Model | MGI Sequence Detail 18686 C57BL/6J ±  kb
    transcript NM_021475 RefSeq | MGI Sequence Detail 2433 C57BL/6  
    polypeptide Q9R0X2 UniProt | EBI | MGI Sequence Detail 467 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 30
      cDNA 30

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2145672
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 4
      Gene Ontology 3
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:326660 Zhao L, et al., Mesenchymal-epithelial interaction regulates gastrointestinal tract development in mouse embryos. Cell Rep. 2022 Jul 12;40(2):111053
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/21/2023
    MGI 6.22     		The Jackson Laboratory