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Tmem185b Gene Detail
Summary
  • Symbol
    Tmem185b
  • Name
    transmembrane protein 185B
  • Synonyms
    2500001K11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917634
    NCBI Gene: 226351
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:119453890-119456713 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 52.31 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    185 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917634
 protein coding gene Chr1:119453884-119456713 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016396
 protein coding gene Chr1:122275536-122278359 (+)
A/J MGP_AJ_G0016379
 protein coding gene Chr1:117896788-117899611 (+)
AKR/J MGP_AKRJ_G0016344
 protein coding gene Chr1:121376796-121379619 (+)
BALB/cJ MGP_BALBcJ_G0016339
 protein coding gene Chr1:118161517-118164340 (+)
C3H/HeJ MGP_C3HHeJ_G0016165
 protein coding gene Chr1:121549968-121552791 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016800
 protein coding gene Chr1:126965559-126968382 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014513
 protein coding gene Chr1:111565685-111568506 (+)
CAST/EiJ MGP_CASTEiJ_G0015746
 protein coding gene Chr1:120316293-120319117 (+)
CBA/J MGP_CBAJ_G0016138
 protein coding gene Chr1:131337018-131339841 (+)
DBA/2J MGP_DBA2J_G0016244
 protein coding gene Chr1:116916910-116919733 (+)
FVB/NJ MGP_FVBNJ_G0016243
 protein coding gene Chr1:115660521-115663344 (+)
LP/J MGP_LPJ_G0016315
 protein coding gene Chr1:123615620-123618443 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016268
 protein coding gene Chr1:137057072-137059895 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016836
 protein coding gene Chr1:121082828-121085651 (+)
PWK/PhJ MGP_PWKPhJ_G0015532
 protein coding gene Chr1:115905629-115908451 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015320
 protein coding gene Chr1:119977254-119980078 (+)
WSB/EiJ MGP_WSBEiJ_G0015808
 protein coding gene Chr1:120969751-120972574 (+)



Homology
more
  • Human Ortholog
    TMEM185B, transmembrane protein 185B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM185B, transmembrane protein 185B
  • Synonyms
    FAM11B
  • Links
    NCBI Gene ID: 79134
    UniProt: Q9H7F4

  • Chr Location
    2q14.2; chr2:120217479-120223400 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000098923 Ensembl Gene Model | MGI Sequence Detail 2824 C57BL/6J ±  kb
    transcript ENSMUST00000183952 Ensembl | MGI Sequence Detail 2824 Not Applicable  
    polypeptide ENSMUSP00000139021 Ensembl | MGI Sequence Detail 350 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 4
    References
    more
    • Summaries
      All 27
      Phenotypes 9
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:131693 Maurer MH, et al., Cloning of a novel neuronally expressed orphan G-protein-coupled receptor which is up-regulated by erythropoietin, interacts with microtubule-associated protein 1b and colocalizes with the 5-hydroxytryptamine 2a receptor. J Neurochem. 2004 Nov;91(4):1007-17
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory