Fam162a MGI Mouse Gene Detail - MGI:1917436 - family with sequence similarity 162, member A

Symbol

Fam162a
Name

family with sequence similarity 162, member A
Synonyms

2310056P07Rik

Feature Type

protein coding gene
IDs

MGI:1917436
NCBI Gene: 70186
Alliance

gene page
Transcription Start Sites

4 TSS

Sequence Map

Chr16:35864214-35891931 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 16, 25.43 cM, cytoband B3
Mapping Data

2 experiments

SNPs within 2kb

263 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1917436	protein coding gene	Chr16:35864131-35891964 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0022777	protein coding gene	Chr16:34411443-34441403 (-)
A/J	MGP_AJ_G0022742	protein coding gene	Chr16:32736663-32765247 (-)
AKR/J	MGP_AKRJ_G0022715	protein coding gene	Chr16:33887694-33916829 (-)
BALB/cJ	MGP_BALBcJ_G0022744	protein coding gene	Chr16:32857329-32885388 (-)
C3H/HeJ	MGP_C3HHeJ_G0022509	protein coding gene	Chr16:34011512-34039208 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0023193	protein coding gene	Chr16:35149323-35178101 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020711	protein coding gene	Chr16:33093708-33118656 (-)
CAST/EiJ	MGP_CASTEiJ_G0022037	protein coding gene	Chr16:34240824-34269049 (-)
CBA/J	MGP_CBAJ_G0022479	protein coding gene	Chr16:36574001-36605696 (-)
DBA/2J	MGP_DBA2J_G0022612	protein coding gene	Chr16:32559642-32586508 (-)
FVB/NJ	MGP_FVBNJ_G0022587	protein coding gene	Chr16:32553869-32581651 (-)
LP/J	MGP_LPJ_G0022679	protein coding gene	Chr16:34137738-34167644 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0022606	protein coding gene	Chr16:35839380-35869765 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0023205	protein coding gene	Chr16:33947083-33975380 (-)
PWK/PhJ	MGP_PWKPhJ_G0021778	protein coding gene	Chr16:32978679-33005806 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0021609	protein coding gene	Chr16:33748074-33775707 (-)
WSB/EiJ	MGP_WSBEiJ_G0022081	protein coding gene	Chr16:33871912-33898895 (-)

Human Ortholog

FAM162A, family with sequence similarity 162 member A

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

FAM162A, family with sequence similarity 162 member A
Synonyms

C3orf28, E2IG5, HGTD-P
Links

HGNC:17865

NCBI Gene ID: 26355

neXtProt AC: NX_Q96A26

UniProt: Q96A26
Chr Location

3q21.1; chr3:122384161-122412334 (+) GRCh38

Alliance of Genome Resources

Fam162a stringent orthology
1 human;1 mouse;2 rat;1 zebrafish
HCOP

vertebrate homology predictions: FAM162A
Gene Tree

Fam162a

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Phenotype Summary

8 phenotypes from 1 allele in 1 genetic background
11 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

All Mutations and Alleles

52
Endonuclease-mediated

1
Gene trapped

47
Targeted

3
Genomic Mutations

1 involving Fam162a
Find Mice (IMSR)

32 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

17
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development	DNA-templated transcription

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

4

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

GEISHA FAM162A

Xenbase fam162a

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Fam162a interacts with 45 markers (Mir19a, Mir19b-1, Mir19b-2, ...) View All

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All Sequences

37
RefSeq

2
UniProt

2
CCDS

CCDS28146.1

Ensembl

ENSMUSG00000003955 (Evidence)
NCBI Gene

70186

			Length	Strain/Species	Flank
genomic	70186	NCBI Gene Model \| MGI Sequence Detail	27718	C57BL/6J	± kb
transcript	NM_027342	RefSeq \| MGI Sequence Detail	681	C57BL/6
polypeptide	Q9D6U8	UniProt \| EBI \| MGI Sequence Detail	155	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000030353 protein FAM162A

(term hierarchy)
InterPro Domains

IPR009432 Protein of unknown function DUF1075

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All nucleic 4

cDNA 4

Microarray probesets 3

Summaries

All 35

Gene Ontology 6

Phenotypes 11
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

TSS for Fam162a:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr140980	Chr16:35892601-35892604 (-)	-672 bp
Tssr140979	Chr16:35892104-35892129 (-)	-186 bp
Tssr140978	Chr16:35891892-35891974 (-)	-2 bp
Tssr4864	Chr16:35868472-35868476 (-)	23,457 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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