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Golm1 Gene Detail
Summary
  • Symbol
    Golm1
  • Name
    golgi membrane protein 1
  • Synonyms
    2310001L02Rik, D030064E01Rik, Golph2, GP73, PSEC0257
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917329
    NCBI Gene: 105348
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:59782810-59823598 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 31.87 cM, cytoband B3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2457 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917329
 protein coding gene Chr13:59782440-59823625 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020639
 protein coding gene Chr13:59343483-59384656 (-)
A/J MGP_AJ_G0020593
 protein coding gene Chr13:57127735-57169212 (-)
AKR/J MGP_AKRJ_G0020571
 protein coding gene Chr13:58835694-58878047 (-)
BALB/cJ MGP_BALBcJ_G0020589
 protein coding gene Chr13:57387958-57428857 (-)
C3H/HeJ MGP_C3HHeJ_G0020388
 protein coding gene Chr13:58627874-58668969 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021023
 protein coding gene Chr13:61133470-61176067 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018605
 protein coding gene Chr13:55019648-55062321 (-)
CAST/EiJ MGP_CASTEiJ_G0019904
 protein coding gene Chr13:58832104-58875336 (-)
CBA/J MGP_CBAJ_G0020348
 protein coding gene Chr13:63444564-63486909 (-)
DBA/2J MGP_DBA2J_G0020471
 protein coding gene Chr13:56674538-56710311 (-)
FVB/NJ MGP_FVBNJ_G0020450
 protein coding gene Chr13:56155807-56196509 (-)
LP/J MGP_LPJ_G0020547
 protein coding gene Chr13:59604063-59647660 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020479
 protein coding gene Chr13:62749325-62791012 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021066
 protein coding gene Chr13:58438911-58480297 (-)
PWK/PhJ MGP_PWKPhJ_G0019658
 protein coding gene Chr13:56699401-56740715 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019485
 protein coding gene Chr13:57322255-57363117 (-)
WSB/EiJ MGP_WSBEiJ_G0019964
 protein coding gene Chr13:58886092-58927805 (-)



Homology
more
  • Human Ortholog
    GOLM1, golgi membrane protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GOLM1, golgi membrane protein 1
  • Synonyms
    bA379P1.3, C9orf155, GOLPH2, GP73, HEL46, PSEC0257
  • Links
    NCBI Gene ID: 51280
    UniProt: Q8NBJ4

  • Chr Location
    9q21.33; chr9:86026146-86100173 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotypes from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele exhibit increased premature lethality with kidney abnormalities and liver steatosis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    1
  • cDNA Data
    136
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 105348 NCBI Gene Model | MGI Sequence Detail 40789 C57BL/6J ±  kb
    transcript NM_027307 RefSeq | MGI Sequence Detail 3693 C57BL/6  
    polypeptide Q91XA2 UniProt | EBI | MGI Sequence Detail 393 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 136
      cDNA 136

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2145419
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 1
      Gene Ontology 4
      Phenotypes 20
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:361188 Huang F, et al., PTEN deficiency potentiates HBV-associated liver cancer development through augmented GP73/GOLM1. J Transl Med. 2024 Mar 8;22(1):254
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory