Golm1 MGI Mouse Gene Detail - MGI:1917329

Symbol

Golm1
Name

golgi membrane protein 1
Synonyms

2310001L02Rik, D030064E01Rik, Golph2, GP73, PSEC0257

Feature Type

protein coding gene
IDs

MGI:1917329
NCBI Gene: 105348
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr13:59782810-59823598 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 31.87 cM, cytoband B3
Mapping Data

3 experiments

SNPs within 2kb

414 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1917329	protein coding gene	Chr13:59782440-59823625 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0020639	protein coding gene	Chr13:59343483-59384656 (-)
A/J	MGP_AJ_G0020593	protein coding gene	Chr13:57127735-57169212 (-)
AKR/J	MGP_AKRJ_G0020571	protein coding gene	Chr13:58835694-58878047 (-)
BALB/cJ	MGP_BALBcJ_G0020589	protein coding gene	Chr13:57387958-57428857 (-)
C3H/HeJ	MGP_C3HHeJ_G0020388	protein coding gene	Chr13:58627874-58668969 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0021023	protein coding gene	Chr13:61133470-61176067 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018605	protein coding gene	Chr13:55019648-55062321 (-)
CAST/EiJ	MGP_CASTEiJ_G0019904	protein coding gene	Chr13:58832104-58875336 (-)
CBA/J	MGP_CBAJ_G0020348	protein coding gene	Chr13:63444564-63486909 (-)
DBA/2J	MGP_DBA2J_G0020471	protein coding gene	Chr13:56674538-56710311 (-)
FVB/NJ	MGP_FVBNJ_G0020450	protein coding gene	Chr13:56155807-56196509 (-)
LP/J	MGP_LPJ_G0020547	protein coding gene	Chr13:59604063-59647660 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020479	protein coding gene	Chr13:62749325-62791012 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021066	protein coding gene	Chr13:58438911-58480297 (-)
PWK/PhJ	MGP_PWKPhJ_G0019658	protein coding gene	Chr13:56699401-56740715 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0019485	protein coding gene	Chr13:57322255-57363117 (-)
WSB/EiJ	MGP_WSBEiJ_G0019964	protein coding gene	Chr13:58886092-58927805 (-)

Human Ortholog

GOLM1, golgi membrane protein 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

GOLM1, golgi membrane protein 1
Synonyms

bA379P1.3, C9orf155, GOLPH2, GP73, HEL46, PSEC0257
Links

HGNC:15451

NCBI Gene ID: 51280

neXtProt AC: NX_Q8NBJ4

UniProt: Q8NBJ4
Chr Location

9q21.33; chr9:86026141-86100201 (-) GRCh38.p7

Alliance of Genome Resources

Golm1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: GOLM1
Gene Tree

Golm1

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Phenotype Summary

17 phenotypes from 1 allele in 1 genetic background
3 phenotypes from multigenic genotypes
18 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

All Mutations and Alleles

158
Chemically induced (other)

1
Endonuclease-mediated

4
Gene trapped

151
Targeted

2
Genomic Mutations

1 involving Golm1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

79 strains or lines available
Comparison Matrix

Gene Expression + Phenotype
Recombinase Activity

Comparison Matrix Gene Expression + Recombinase Activity

Mice homozygous for a gene trap allele exhibit increased premature lethality with kidney abnormalities and liver steatosis.

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All GO Annotations

7
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

707
Tissues

1
cDNA Data

136
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase golm1

ZFIN golm1

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Golm1 interacts with 263 markers (Mir10a, Mir10b, Mir15a, ...) View All

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All Sequences

50
RefSeq

4
UniProt

4
CCDS

CCDS26576.1

Ensembl

ENSMUSG00000021556 (Evidence)
NCBI Gene

105348

			Length	Strain/Species	Flank
genomic	105348	NCBI Gene Model \| MGI Sequence Detail	40789	C57BL/6J	± kb
transcript	NM_027307	RefSeq \| MGI Sequence Detail	3693	C57BL/6
polypeptide	Q91XA2	UniProt \| EBI \| MGI Sequence Detail	393	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000008141 Golgi membrane protein 1

(term hierarchy)
InterPro Domains

IPR026139 GOLM1/CASC4 family

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All nucleic 136

cDNA 136

Microarray probesets 3

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MGI:2145419

Summaries

All 49

Developmental Gene Expression 1

Gene Ontology 5

Phenotypes 18
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:335014 Wan L, et al., GP73 is a glucogenic hormone contributing to SARS-CoV-2-induced hyperglycemia. Nat Metab. 2022 Jan;4(1):29-43

TSS for Golm1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr122877	Chr13:59823568-59823628 (-)	0 bp
Tssr122876	Chr13:59819823-59819827 (-)	3,773 bp
Tssr4093	Chr13:59788029-59788051 (-)	35,558 bp
Tssr122875	Chr13:59787993-59788003 (-)	35,600 bp
Tssr122874	Chr13:59787967-59787986 (-)	35,621 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Copyright, and Privacy Statement Send questions and comments to User Support.	last database update 05/30/2023 MGI 6.22