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Spata3 Gene Detail
Summary
  • Symbol
    Spata3
  • Name
    spermatogenesis associated 3
  • Synonyms
    1700011N12Rik, 1700029H01Rik, 4930424D10Rik, TSARG1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917310
    NCBI Gene: 70060
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:85945728-85957683 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 43.94 cM, cytoband C5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    88 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917310
 protein coding gene Chr1:85944538-85957683 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016239
 protein coding gene Chr1:87246355-87259498 (+)
A/J MGP_AJ_G0016220
 protein coding gene Chr1:84021596-84035731 (+)
AKR/J MGP_AKRJ_G0016181
 protein coding gene Chr1:86453254-86466262 (+)
BALB/cJ MGP_BALBcJ_G0016177
 protein coding gene Chr1:84137188-84150330 (+)
C3H/HeJ MGP_C3HHeJ_G0016005
 protein coding gene Chr1:86706030-86719259 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016633
 protein coding gene Chr1:90577766-90590908 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014355
 protein coding gene Chr1:78509312-78522341 (+)
CAST/EiJ MGP_CASTEiJ_G0015590
 protein coding gene Chr1:85941877-85956585 (+)
CBA/J MGP_CBAJ_G0015981
 protein coding gene Chr1:93392524-93405750 (+)
DBA/2J MGP_DBA2J_G0016084
 protein coding gene Chr1:83330964-83344098 (+)
FVB/NJ MGP_FVBNJ_G0016083
 protein coding gene Chr1:82375310-82388551 (+)
LP/J MGP_LPJ_G0016155
 protein coding gene Chr1:88363147-88371228 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016109
 protein coding gene Chr1:96679391-96692405 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016676
 protein coding gene Chr1:86578959-86592200 (+)
PWK/PhJ MGP_PWKPhJ_G0015377
 protein coding gene Chr1:82608706-82622090 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015157
 protein coding gene Chr1:85557608-85570673 (+)
WSB/EiJ MGP_WSBEiJ_G0015654
 protein coding gene Chr1:86226801-86239944 (+)



Homology
more
  • Human Ortholog
    SPATA3, spermatogenesis associated 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPATA3, spermatogenesis associated 3
  • Synonyms
    TSARG1
  • Links
    NCBI Gene ID: 130560
    neXtProt AC: NX_Q8NHX4
    UniProt: Q8NHX4

  • Chr Location
    2q37.1; chr2:230990324-231025055 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit normal fertility in vivo, but reduced male fertilization rates in vitro.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    25
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 70060 NCBI Gene Model | MGI Sequence Detail 11956 C57BL/6J ±  kb
    transcript NM_027300 RefSeq | MGI Sequence Detail 1107 C57BL/6  
    polypeptide Q9D9T6 UniProt | EBI | MGI Sequence Detail 193 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 25
      cDNA 25

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1916552, MGI:1921026
    References
    more
    • Summaries
      All 26
      Phenotypes 8
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:305339 Girault MS, et al., Deletion of the Spata3 Gene Induces Sperm Alterations and In Vitro Hypofertility in Mice. Int J Mol Sci. 2021 Feb 16;22(4)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory