Dancr Gene Detail

Summary

• Symbol
  Dancr
• Name
  differentiation antagonizing non-protein coding RNA
• Synonyms
  2700023E23Rik

• Feature Type
  lncRNA gene
• IDs
  MGI:1917286
  NCBI Gene: 70036
• Alliance
  genome feature page
• Transcription Start Sites
  4 TSS

Location &
Maps

• Sequence Map
  Chr5:74253780-74254998 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 39.38 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  121 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1917286	lncRNA gene	Chr5:74253357-74284805 (+)
129S1/SvImJ	ENSMUSG00200036678	lncRNA gene	Chr5:69926366-69928735 (+)
A/J	ENSMUSG00195035159	lncRNA gene	Chr5:69244088-69246459 (+)
AKR/J	ENSMUSG00220004992	lncRNA gene	Chr5:69349555-69351924 (+)
BALB/cJ	ENSMUSG00180026322	lncRNA gene	Chr5:69001125-69003495 (+)
C3H/HeJ	ENSMUSG00175028522	lncRNA gene	Chr5:71060585-71062965 (+)
C57BL/6NJ	ENSMUSG00215006461	lncRNA gene	Chr5:69829354-69831726 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0006060	lincRNA gene	Chr5:67015891-67018221 (+)
CAST/EiJ	ENSTCUG00005032759	lncRNA gene	Chr5:68811277-68813661 (+)
CBA/J	ENSMUSG00210023647	lncRNA gene	Chr5:69998670-70001050 (+)
DBA/2J	ENSMUSG00185016650	lncRNA gene	Chr5:71828493-71830873 (+)
FVB/NJ	ENSMUSG00205032783	lncRNA gene	Chr5:68767207-68769577 (+)
JF1/MsJ	ENSUMUG00000006713	lncRNA gene	Chr5:76312962-76315345 (+)
LP/J	ENSMUSG00230022208	lncRNA gene	Chr5:76500593-76502963 (+)
NOD/ShiLtJ	ENSMUSG00190004663	lncRNA gene	Chr5:68943437-68945807 (+)
NZO/HlLtJ	ENSMUSG00225034201	lncRNA gene	Chr5:81564255-81566627 (+)
PWK/PhJ	ENSLUMG00010014486	lncRNA gene	Chr5:68872150-68874527 (+)
SPRET/EiJ	ENSMSPG00010010269	lncRNA gene	Chr5:70893541-70895906 (+)
WSB/EiJ	ENSIUOG00005018478	lncRNA gene	Chr5:71766054-71768421 (+)

Homology

• Human Ortholog
  DANCR, differentiation antagonizing non-protein coding RNA

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  DANCR, differentiation antagonizing non-protein coding RNA
  
• Synonyms
  AGU2, ANCR, KIAA0114, lncRNA-ANCR, SNHG13
• Links
  HGNC:28964

  NCBI Gene ID: 57291

  
  
• Chr Location
  4q12; chr4:52712325-52723623 (+)  GRCh38

---

• MGI Vertebrate Homology
  Dancr stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: DANCR
• Gene Tree
  Dancr
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 1 allele in 1 genetic background
  401 phenotype references
  

• All Mutations and Alleles
  46
• Chemically induced (other)
  2
• Endonuclease-mediated
  4
• Gene trapped
  36
• Radiation induced
  1
• Spontaneous
  3
• Genomic Mutations
  6 involving Dancr
• Find Mice (IMSR)
  30 strains or lines available
• Comparison Matrix
  Gene Expression + Phenotype

Homozygous mice for a null allele exhibit reduced hepatocellular carcinoma development and hepatic fibrosis in a DEN-CCl4-induced carcinogenesis model.

Expression

• Assay Results
  616
• Tissues
  17
• cDNA Data
  7
• Literature Summary
  1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  42
• RefSeq
  3
• UniProt
  1

• Ensembl
  ENSMUSG00000106943 (Evidence)
• NCBI Gene
  70036

Representative Sequences			Length	Strain/Species
genomic	70036	NCBI Gene Model | MGI Sequence Detail	1219	C57BL/6J
transcript	NR_145133	RefSeq | MGI Sequence Detail	1219	C57BL/6
polypeptide	Q3T987	UniProt | EBI | MGI Sequence Detail	203	Not Applicable

Protein
Information

• UniProt
  1 Sequence

Molecular
Reagents

• All nucleic 9

  cDNA 8

  Primer pair 1

  
  

  Microarray probesets 3

References

• Summaries
  All 420

  Developmental Gene Expression 1

  Diseases 1

  Phenotypes 401
• Earliest
  J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
• Latest
  J:390040 Dang L, et al., Activation of Intestinal Mast Cells Contributes to Gut Damage After Cardiac Arrest in Mice. Shock. 2026 Jan 1;65(1):85-92

TSS for Dancr:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr46666	Chr5:74253722-74253733 (+)	-52 bp
Tssr46667	Chr5:74253736-74253761 (+)	-31 bp
Tssr46668	Chr5:74253773-74253790 (+)	2 bp
Tssr46669	Chr5:74253793-74253800 (+)	17 bp