Slc23a4 MGI Mouse Gene Detail - MGI:1917272 - solute carrier family 23 member 4

Symbol

Slc23a4
Name

solute carrier family 23 member 4
Synonyms

2010107G12Rik, LOC243753

Feature Type

protein coding gene
IDs

MGI:1917272
NCBI Gene: 243753
Alliance

genome feature page
Transcription Start Sites

1 TSS

Sequence Map

Chr6:34922213-34965339 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 6, 15.20 cM
Mapping Data

1 experiment

SNPs within 2kb

1388 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1917272	protein coding gene	Chr6:34922213-34965430 (-)
129S1/SvImJ	ENSMUSG00200042735	protein coding gene	Chr6:31976383-32019513 (-)
A/J	ENSMUSG00195035559	protein coding gene	Chr6:31943719-31986850 (-)
AKR/J	ENSMUSG00220008744	protein coding gene	Chr6:31545068-31588205 (-)
BALB/cJ	ENSMUSG00180044444	protein coding gene	Chr6:32075341-32118474 (-)
C3H/HeJ	ENSMUSG00175046412	protein coding gene	Chr6:31941963-31985093 (-)
C57BL/6NJ	ENSMUSG00215047287	protein coding gene	Chr6:31977013-32020139 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0028216	protein coding gene	Chr6:29728085-29769376 (-)
CAST/EiJ	ENSTCUG00005032907	protein coding gene	Chr6:31520424-31559345 (-)
CBA/J	ENSMUSG00210052024	protein coding gene	Chr6:31975558-32018697 (-)
DBA/2J	ENSMUSG00185042508	protein coding gene	Chr6:32053429-32096563 (-)
FVB/NJ	ENSMUSG00205049090	protein coding gene	Chr6:32033729-32076866 (-)
JF1/MsJ	ENSUMUG00000021063	protein coding gene	Chr6:31751286-31792921 (-)
LP/J	ENSMUSG00230039455	protein coding gene	Chr6:32992666-33035801 (-)
NOD/ShiLtJ	ENSMUSG00190035179	protein coding gene	Chr6:31827876-31870996 (-)
NZO/HlLtJ	ENSMUSG00225009061	protein coding gene	Chr6:34962037-35005159 (-)
PWK/PhJ	ENSLUMG00010041258	protein coding gene	Chr6:31513069-31554649 (-)
SPRET/EiJ	ENSMSPG00010025598	protein coding gene	Chr6:32081920-32126630 (-)
WSB/EiJ	ENSIUOG00005028877	protein coding gene	Chr6:32127867-32170971 (-)

Human Ortholog

SLC23A4P, solute carrier family 23 member 4, pseudogene

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SLC23A4P, solute carrier family 23 member 4, pseudogene
Synonyms

SLC23A4
Links

HGNC:20602

NCBI Gene ID: 641842
Chr Location

chr7:135277217-135313561 (-) GRCh38

MGI Vertebrate Homology

Slc23a4 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: SLC23A4P
Gene Tree

Slc23a4

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
8 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

9
Endonuclease-mediated

5
Targeted

4
Incidental Mutations

CvDC
Find Mice (IMSR)

25 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

6
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

10

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

GEO

Expression Atlas
Other Vertebrate Links

ZFIN slc23a4

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All Sequences

45
RefSeq

6
UniProt

5
CCDS

CCDS19998.1

Ensembl

ENSMUSG00000029847 (Evidence)
NCBI Gene

243753

			Length	Strain/Species	Flank
genomic	ENSMUSG00000029847	Ensembl Gene Model \| MGI Sequence Detail	43127	C57BL/6J	± kb
transcript	ENSMUST00000201355	Ensembl \| MGI Sequence Detail	2003	Not Applicable
polypeptide	ENSMUSP00000144387	Ensembl \| MGI Sequence Detail	615	Not Applicable

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UniProt

5 Sequences
InterPro Domains

IPR006043 Nucleobase cation symporter 2 family

IPR006042 Xanthine/uracil permease

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All nucleic 10

cDNA 10

Microarray probesets 2

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MGI:2685314

Summaries

All 28

Gene Ontology 3

Phenotypes 8
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:361518 Terada K, et al., Pseudogenization of the Slc23a4 gene is necessary for the survival of Xdh-deficient mice. Sci Rep. 2025 Jan 25;15(1):3250

TSS for Slc23a4:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr60270	Chr6:34965373-34965390 (-)	-43 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/08/2026 MGI 6.24