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Cfap74 Gene Detail
Summary
  • Symbol
    Cfap74
  • Name
    cilia and flagella associated protein 74
  • Synonyms
    2010015L04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917130
    NCBI Gene: 544678
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:155493647-155551280 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 86.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1781 from dbSNP Build 142
  • Strain Annotations
    26
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917130
 protein coding gene Chr4:155493647-155551280 (+)
129S1/SvImJ ENSMUSGG00200054807
 protein coding gene Chr4:146603285-146605846 (+)
129S1/SvImJ ENSMUSG00200019034
 protein coding gene Chr4:146555156-146561442 (+)
A/J ENSMUSG00195017381
 protein coding gene Chr4:148221169-148227453 (+)
A/J ENSMUSGG00195054990
 protein coding gene Chr4:148269310-148271871 (+)
AKR/J ENSMUSGG00220054756
 protein coding gene Chr4:147844773-147847334 (+)
AKR/J ENSMUSG00220026193
 protein coding gene Chr4:147796630-147802914 (+)
BALB/cJ ENSMUSGG00180055378
 protein coding gene Chr4:145923957-145926518 (+)
BALB/cJ ENSMUSG00180002272
 protein coding gene Chr4:145875861-145882145 (+)
C3H/HeJ ENSMUSGG00175054720
 protein coding gene Chr4:149224558-149227119 (+)
C3H/HeJ ENSMUSG00175018263
 protein coding gene Chr4:149176439-149182723 (+)
C57BL/6NJ ENSMUSGG00215055372
 protein coding gene Chr4:148071007-148073568 (+)
C57BL/6NJ ENSMUSG00215008543
 protein coding gene Chr4:148022828-148029142 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026889
 protein coding gene Chr4:145319774-145377535 (+)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210054584
 protein coding gene Chr4:147882890-147885451 (+)
CBA/J ENSMUSG00210003958
 protein coding gene Chr4:147834769-147841053 (+)
DBA/2J ENSMUSGG00185057521
 protein coding gene Chr4:151440503-151443064 (+)
DBA/2J ENSMUSG00185015818
 protein coding gene Chr4:151392377-151398661 (+)
FVB/NJ ENSMUSGG00205054586
 protein coding gene Chr4:146335769-146338330 (+)
FVB/NJ ENSMUSG00205017130
 protein coding gene Chr4:146288471-146293373 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230020066
 protein coding gene Chr4:158118128-158124414 (+)
LP/J ENSMUSGG00230055471
 protein coding gene Chr4:158165946-158168507 (+)
NOD/ShiLtJ ENSMUSG00190003727
 protein coding gene Chr4:147492297-147497201 (+)
NOD/ShiLtJ ENSMUSGG00190054661
 protein coding gene Chr4:147539586-147542147 (+)
NZO/HlLtJ ENSMUSG00225024338
 protein coding gene Chr4:162114999-162121283 (+)
NZO/HlLtJ ENSMUSGG00225055609
 protein coding gene Chr4:162163114-162165675 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CFAP74, cilia and flagella associated protein 74
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CFAP74, cilia and flagella associated protein 74
  • Synonyms
    C1orf222, CILD49, KIAA1751
  • Links
    NCBI Gene ID: 85452
    UniProt: Q9C0B2

  • Chr Location
    1p36.33; chr1:1921951-2003837 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CFAP74 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 544678 NCBI Gene Model | MGI Sequence Detail 57634 C57BL/6J ±  kb
transcript NM_001368738 RefSeq | MGI Sequence Detail 5640 C57BL/6  
polypeptide Q3UY96 UniProt | EBI | MGI Sequence Detail 1578 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 2
References
more
  • Summaries
    All 29
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory