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Cfap74 Gene Detail
Summary
  • Symbol
    Cfap74
  • Name
    cilia and flagella associated protein 74
  • Synonyms
    2010015L04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917130
    NCBI Gene: 544678
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:155493647-155551280 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 86.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    354 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917130
 protein coding gene Chr4:155493647-155551280 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029213
 protein coding gene Chr4:159733384-159799587 (+)
A/J MGP_AJ_G0029178
 protein coding gene Chr4:153026012-153086206 (+)
AKR/J MGP_AKRJ_G0029126
 protein coding gene Chr4:157185292-157245834 (+)
BALB/cJ MGP_BALBcJ_G0029194
 protein coding gene Chr4:153496448-153555860 (+)
C3H/HeJ MGP_C3HHeJ_G0028915
 protein coding gene Chr4:157728084-157791852 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029643
 protein coding gene Chr4:165420416-165487949 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026889
 protein coding gene Chr4:145319774-145377535 (+)
CAST/EiJ MGP_CASTEiJ_G0028328
 protein coding gene Chr4:155167405-155228296 (+)
CBA/J MGP_CBAJ_G0028877
 protein coding gene Chr4:170394506-170475825 (+)
DBA/2J MGP_DBA2J_G0029026
 protein coding gene Chr4:153041133-153105647 (+)
FVB/NJ MGP_FVBNJ_G0028990
 protein coding gene Chr4:152284090-152345036 (+)
LP/J MGP_LPJ_G0029116
 protein coding gene Chr4:159658222-159722796 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029017
 protein coding gene Chr4:173241413-173304731 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029675
 protein coding gene Chr4:157796920-157864585 (+)
PWK/PhJ MGP_PWKPhJ_G0028048
 protein coding gene Chr4:149176301-149239996 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027882
 protein coding gene Chr4:152066508-152126880 (+)
WSB/EiJ MGP_WSBEiJ_G0028408
 protein coding gene Chr4:157970749-158038164 (+)



Homology
more
  • Human Ortholog
    CFAP74, cilia and flagella associated protein 74
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CFAP74, cilia and flagella associated protein 74
  • Synonyms
    C1orf222, CILD49, KIAA1751
  • Links
    NCBI Gene ID: 85452
    neXtProt AC: NX_Q9C0B2
    UniProt: Q9C0B2

  • Chr Location
    1p36.33; chr1:1921951-2003837 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 544678 NCBI Gene Model | MGI Sequence Detail 57634 C57BL/6J ±  kb
transcript NM_001368738 RefSeq | MGI Sequence Detail 5640 C57BL/6  
polypeptide Q3UY96 UniProt | EBI | MGI Sequence Detail 1578 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/30/2023
MGI 6.22 		The Jackson Laboratory