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Ddx51 Gene Detail
Summary
  • Symbol
    Ddx51
  • Name
    DEAD box helicase 51
  • Synonyms
    2310061O04Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916913
    NCBI Gene: 69663
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:110801317-110808362 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 53.69 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    208 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916913
 protein coding gene Chr5:110801298-110810885 (+)
129S1/SvImJ ENSMUSG00200022506
 protein coding gene Chr5:104568608-104575654 (+)
A/J ENSMUSG00195029962
 protein coding gene Chr5:104051600-104058645 (+)
AKR/J ENSMUSG00220043471
 protein coding gene Chr5:103571151-103578196 (+)
BALB/cJ ENSMUSG00180038710
 protein coding gene Chr5:104203349-104210394 (+)
C3H/HeJ ENSMUSG00175035438
 protein coding gene Chr5:106189354-106196399 (+)
C57BL/6NJ ENSMUSG00215017163
 protein coding gene Chr5:104198829-104205874 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027549
 protein coding gene Chr5:103577497-103585193 (+)
CAST/EiJ ENSTCUG00005029649
 protein coding gene Chr5:103384988-103392056 (+)
CBA/J ENSMUSG00210041511
 protein coding gene Chr5:104941494-104948539 (+)
DBA/2J ENSMUSG00185043392
 protein coding gene Chr5:107968497-107975542 (+)
FVB/NJ ENSMUSG00205026854
 protein coding gene Chr5:103841029-103848074 (+)
JF1/MsJ ENSUMUG00000007205
 protein coding gene Chr5:110818268-110825687 (+)
LP/J ENSMUSG00230047787
 protein coding gene Chr5:112107073-112114119 (+)
NOD/ShiLtJ ENSMUSG00190043243
 protein coding gene Chr5:103877219-103884264 (+)
NZO/HlLtJ ENSMUSG00225024730
 protein coding gene Chr5:119728927-119735973 (+)
PWK/PhJ ENSLUMG00010028292
 protein coding gene Chr5:102725136-102732550 (+)
SPRET/EiJ ENSMSPG00010043668
 protein coding gene Chr5:105975341-105982354 (+)
WSB/EiJ ENSIUOG00005040589
 protein coding gene Chr5:106580768-106587813 (+)



Homology
more
  • Human Ortholog
    DDX51, DEAD-box helicase 51
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DDX51, DEAD-box helicase 51
  • Links
    NCBI Gene ID: 317781
    UniProt: Q8N8A6

  • Chr Location
    12q24.33; chr12:132136591-132144335 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    598
  • Tissues
    1
  • cDNA Data
    10
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000029504 Ensembl Gene Model | MGI Sequence Detail 7046 C57BL/6J ±  kb
    transcript ENSMUST00000031478 Ensembl | MGI Sequence Detail 4846 Not Applicable  
    polypeptide ENSMUSP00000031478 Ensembl | MGI Sequence Detail 639 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 10

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2140771, MGI:2141325, MGI:2141352
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 10
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory