2300002M23Rik MGI Mouse Gene Detail - MGI:1916792

Symbol

2300002M23Rik
Name

RIKEN cDNA 2300002M23 gene
Synonyms

emprin

Feature Type

protein coding gene
IDs

MGI:1916792
NCBI Gene: 69542
Alliance

genome feature page
Transcription Start Sites

4 TSS

Sequence Map

Chr17:35878382-35879842 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 17, 18.70 cM
Mapping Data

1 experiment

Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1916792	protein coding gene	Chr17:35878347-35879849 (+)
129S1/SvImJ	ENSMUSG00200049445	protein coding gene	Chr17:31488818-31490320 (+)
A/J	ENSMUSG00195044970	protein coding gene	Chr17:32571272-32572774 (+)
AKR/J	ENSMUSG00220037132	protein coding gene	Chr17:31359028-31360529 (+)
BALB/cJ	ENSMUSG00180030842	protein coding gene	Chr17:31941088-31942590 (+)
C3H/HeJ	ENSMUSG00175036289	protein coding gene	Chr17:31244876-31246377 (+)
C57BL/6NJ	ENSMUSG00215052327	protein coding gene	Chr17:31328842-31330344 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0021525	protein coding gene	Chr17:32345363-32346970 (+)
CAST/EiJ	ENSTCUG00005049451	protein coding gene	Chr17:32394512-32396014 (+)
CBA/J	ENSMUSG00210044441	protein coding gene	Chr17:31066960-31068461 (+)
DBA/2J	ENSMUSG00185041717	protein coding gene	Chr17:33960241-33961743 (+)
FVB/NJ	ENSMUSG00205053211	protein coding gene	Chr17:31624935-31626437 (+)
JF1/MsJ	ENSUMUG00000042245	protein coding gene	Chr17:32901792-32903333 (+)
LP/J	ENSMUSG00230054467	protein coding gene	Chr17:34977528-34979030 (+)
NOD/ShiLtJ	ENSMUSG00190039973	protein coding gene	Chr17:31244102-31245604 (+)
NZO/HlLtJ	ENSMUSG00225051115	protein coding gene	Chr17:37054227-37055729 (+)
PWK/PhJ	ENSLUMG00010033666	protein coding gene	Chr17:30878104-30879642 (+)
SPRET/EiJ	ENSMSPG00010049229	protein coding gene	Chr17:32091939-32093442 (+)
WSB/EiJ	ENSIUOG00005047041	protein coding gene	Chr17:32064009-32065511 (+)

Human Ortholog

C6orf15, chromosome 6 open reading frame 15

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

C6orf15, chromosome 6 open reading frame 15
Synonyms

STG
Links

HGNC:13927

NCBI Gene ID: 29113

UniProt: Q6UXA7
Chr Location

6p21.33; chr6:31111223-31112575 (-) GRCh38

MGI Vertebrate Homology

2300002M23Rik stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: C6orf15
Gene Tree

2300002M23Rik

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
5 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

3
Targeted

3
Genomic Mutations

1 involving 2300002M23Rik
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

15 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Female homozygous null mice exhibit reduced body weight and total body fat.

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All GO Annotations

10
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

598
Tissues

1
cDNA Data

6
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

31
RefSeq

2
UniProt

1
CCDS

CCDS50092.1

Ensembl

ENSMUSG00000039269 (Evidence)
NCBI Gene

69542

			Length	Strain/Species	Flank
genomic	69542	NCBI Gene Model \| MGI Sequence Detail	1461	C57BL/6J	± kb
transcript	NM_175148	RefSeq \| MGI Sequence Detail	1248	C57BL/6
polypeptide	Q8BM15	UniProt \| EBI \| MGI Sequence Detail	349	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000059877 uncharacterized protein C6orf15

(term hierarchy)
InterPro Domains

IPR026135 Uncharacterised protein C6orf15
GlyGen

Q8BM15 1 site, 1 O-linked glycan (1 site)

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All nucleic 7

cDNA 7

Antibodies 1

Microarray probesets 2

Summaries

All 23

Developmental Gene Expression 1

Gene Ontology 1

Phenotypes 5
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:190754 Ermakova O, et al., Construction and phenotypic analysis of mice carrying a duplication of the major histocompatibility class I (MHC-I) locus. Mamm Genome. 2012 Aug;23(7-8):443-53

TSS for 2300002M23Rik:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr5107	Chr17:35878302-35878317 (+)	-72 bp
Tssr5108	Chr17:35878332-35878344 (+)	-44 bp
Tssr144397	Chr17:35878362-35878387 (+)	-7 bp
Tssr144398	Chr17:35878424-35878441 (+)	51 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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