Krtap4-13 Gene Detail

Summary

• Symbol
  Krtap4-13
• Name
  keratin associated protein 4-13
• Synonyms
  2300006N05Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1916714
  NCBI Gene: 69464
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr11:99699904-99700718 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, 63.15 cM, cytoband D
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  2 from dbSNP Build 142
• Strain Annotations
  7

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1916714	protein coding gene	Chr11:99699904-99700722 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0019118	protein coding gene	Chr11:102501284-102502188 (-)
A/J	MGP_AJ_G0019087	protein coding gene	Chr11:98166824-98175491 (-)
AKR/J	MGP_AKRJ_G0019060	protein coding gene	Chr11:101236938-101237827 (-)
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	MGP_DBA2J_G0018954	protein coding gene	Chr11:97753416-97754971 (-)
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	MGP_NODShiLtJ_G0018972	protein coding gene	Chr11:109714945-109715834 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019551	protein coding gene	Chr11:101585478-101586481 (-)
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Human Ortholog
  KRTAP4-3, keratin associated protein 4-3

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  KRTAP4-3, keratin associated protein 4-3
  
• Synonyms
  KAP4.3
• Links
  HGNC:18908

  NCBI Gene ID: 85290

  neXtProt AC: NX_Q9BYR4

  UniProt: Q9BYR4

  
  
• Chr Location
  17q21.2; chr17:41167231-41168221 (-)  GRCh38

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• Human Ortholog
  KRTAP4-9, keratin associated protein 4-9
  
• Synonyms
  KAP4.9
• Links
  HGNC:18910

  NCBI Gene ID: 100132386

  neXtProt AC: NX_Q9BYQ8

  UniProt: Q9BYQ8

  
  
• Chr Location
  17q21.2; chr17:41105389-41106488 (+)  GRCh38

---

• MGI Vertebrate Homology
  Krtap4-13 stringent orthology
  2 human;1 mouse
  
• HCOP
  vertebrate homology predictions: KRTAP4-3, KRTAP4-9
• Gene Tree
  Krtap4-13
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Genomic Mutations
  2 involving Krtap4-13
• Incidental Mutations
  APF
• Find Mice (IMSR)
  6 strains or lines available

Gene Ontology
(GO)
Classifications

Expression

• Assay Results
  706
• cDNA Data
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  15
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS48921.1

• Ensembl
  ENSMUSG00000048294 (Evidence)
• NCBI Gene
  69464

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000048294	Ensembl Gene Model | MGI Sequence Detail	815	C57BL/6J
transcript	ENSMUST00000050106	Ensembl | MGI Sequence Detail	815	Not Applicable
polypeptide	ENSMUSP00000053810	Ensembl | MGI Sequence Detail	165	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR002494 Keratin-associated protein

Molecular
Reagents

• All nucleic 1

  cDNA 1

  
  

  Microarray probesets 1

References

• Summaries
  All 19

  Phenotypes 6
• Earliest
  J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
• Latest
  J:230728 Kumar V, et al., A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75