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Cst12 Gene Detail
Summary
  • Symbol
    Cst12
  • Name
    cystatin 12
  • Synonyms
    1700006F03Rik, cystatin TE-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916612
    NCBI Gene: 69362
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:148631285-148635352 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 73.55 cM, cytoband H1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    333 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916612
 protein coding gene Chr2:148631281-148635466 (+)
129S1/SvImJ ENSMUSG00200026920
 protein coding gene Chr2:145742901-145747086 (+)
A/J ENSMUSG00195018869
 protein coding gene Chr2:145852604-145856786 (+)
AKR/J ENSMUSG00220038661
 protein coding gene Chr2:145456146-145460331 (+)
BALB/cJ ENSMUSG00180040853
 protein coding gene Chr2:145519063-145523248 (+)
C3H/HeJ ENSMUSG00175042902
 protein coding gene Chr2:146066111-146070293 (+)
C57BL/6NJ ENSMUSG00215014322
 protein coding gene Chr2:145598658-145602843 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024414
 protein coding gene Chr2:140907105-140911320 (+)
CAST/EiJ ENSTCUG00005041877
 protein coding gene Chr2:144712859-144718041 (+)
CBA/J ENSMUSG00210039442
 protein coding gene Chr2:145985213-145989395 (+)
DBA/2J ENSMUSG00185048067
 protein coding gene Chr2:145625286-145629468 (+)
FVB/NJ ENSMUSG00205018534
 protein coding gene Chr2:144772836-144777014 (+)
JF1/MsJ ENSUMUG00000039772
 protein coding gene Chr2:145418919-145423104 (+)
LP/J ENSMUSG00230030892
 protein coding gene Chr2:147325341-147329526 (+)
NOD/ShiLtJ ENSMUSG00190026659
 protein coding gene Chr2:145687126-145691311 (+)
NZO/HlLtJ ENSMUSG00225003169
 protein coding gene Chr2:155313921-155318103 (+)
PWK/PhJ ENSLUMG00010038913
 protein coding gene Chr2:145419465-145423639 (+)
SPRET/EiJ ENSMSPG00010026458
 protein coding gene Chr2:147938419-147942611 (+)
WSB/EiJ ENSIUOG00005043914
 protein coding gene Chr2:145427859-145432031 (+)



Homology
more
  • Human Ortholog
    CST12P, cystatin 12, pseudogene
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CST12P, cystatin 12, pseudogene
  • Synonyms
    Cst, Ctes4, E2
  • Links
    NCBI Gene ID: 106478911

  • Chr Location
    20p11.21; chr20:23475700-23479906 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    3 involving Cst12
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    8 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    633
  • Tissues
    29
  • cDNA Data
    19
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69362 NCBI Gene Model | MGI Sequence Detail 4068 C57BL/6J ±  kb
transcript NM_027054 RefSeq | MGI Sequence Detail 537 Not Specified  
polypeptide Q9DAN8 UniProt | EBI | MGI Sequence Detail 128 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    cDNA 19
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:279308 Fujihara Y, et al., Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18498-18506
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory