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Anapc10 Gene Detail
Summary
  • Symbol
    Anapc10
  • Name
    anaphase promoting complex subunit 10
  • Synonyms
    1500026N15Rik, A830003M23Rik, Apc10
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916249
    NCBI Gene: 68999
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:80438366-80503950 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 8, 37.79 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1445 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916249
protein coding gene Chr8:80438366-80505688 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033815
protein coding gene Chr8:80401192-80472681 (+)
A/J MGP_AJ_G0033797
protein coding gene Chr8:77205276-77261139 (+)
AKR/J MGP_AKRJ_G0033724
protein coding gene Chr8:79511722-79568995 (+)
BALB/cJ MGP_BALBcJ_G0033791
protein coding gene Chr8:77319422-77379143 (+)
C3H/HeJ MGP_C3HHeJ_G0033500
protein coding gene Chr8:80145427-80210754 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034311
protein coding gene Chr8:83483281-83553187 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031252
protein coding gene Chr8:71266659-71320944 (+)
CAST/EiJ MGP_CASTEiJ_G0032831
protein coding gene Chr8:79480277-79546311 (+)
CBA/J MGP_CBAJ_G0033479
protein coding gene Chr8:86418731-86486153 (+)
DBA/2J MGP_DBA2J_G0033632
protein coding gene Chr8:76900830-76961981 (+)
FVB/NJ MGP_FVBNJ_G0033577
protein coding gene Chr8:75869155-75926488 (+)
LP/J MGP_LPJ_G0033722
protein coding gene Chr8:80480027-80548600 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033620
protein coding gene Chr8:88980738-89047502 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034328
protein coding gene Chr8:79533850-79594553 (+)
PWK/PhJ MGP_PWKPhJ_G0032534
protein coding gene Chr8:76173251-76237229 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032372
protein coding gene Chr8:78343805-78400544 (+)
WSB/EiJ MGP_WSBEiJ_G0032944
protein coding gene Chr8:79865153-79927801 (+)



Homology
more
  • Human Ortholog
    ANAPC10, anaphase promoting complex subunit 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANAPC10, anaphase promoting complex subunit 10
  • Synonyms
    APC10, DOC1
  • Links
    NCBI Gene ID: 10393
    neXtProt AC: NX_Q9UM13
    UniProt: Q9UM13

  • Chr Location
    4q31.21; chr4:144831908-145098571 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    40 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68999 NCBI Gene Model | MGI Sequence Detail 65585 C57BL/6J ±  kb
    transcript NM_001357236 RefSeq | MGI Sequence Detail 2903 ZRU/MplStud  
    polypeptide Q8K2H6 UniProt | EBI | MGI Sequence Detail 185 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 10

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2441829
    References
    more
    • Summaries
      All 65
      Developmental Gene Expression 3
      Gene Ontology 6
      Phenotypes 40
    • Earliest
      J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    07/05/2024
    MGI 6.24
    The Jackson Laboratory