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Disp1 Gene Detail
Summary
  • Symbol
    Disp1
  • Name
    dispatched RND transporter family member 1
  • Synonyms
    1190008H24Rik, DispA
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916147
    NCBI Gene: 68897
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:182867830-183003086 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, Syntenic
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3795 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916147
protein coding gene Chr1:182867828-183010257 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016900
protein coding gene Chr1:189723406-189861801 (-)
A/J MGP_AJ_G0016879
protein coding gene Chr1:181971646-182108182 (-)
AKR/J MGP_AKRJ_G0016844
protein coding gene Chr1:187377322-187520677 (-)
BALB/cJ MGP_BALBcJ_G0016837
protein coding gene Chr1:182609997-182751231 (-)
C3H/HeJ MGP_C3HHeJ_G0016661
protein coding gene Chr1:188185626-188324703 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017300
protein coding gene Chr1:195807003-195956018 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015007
protein coding gene Chr1:173034917-173165034 (-)
CAST/EiJ MGP_CASTEiJ_G0016243
protein coding gene Chr1:187559059-187713237 (-)
CBA/J MGP_CBAJ_G0016635
protein coding gene Chr1:203094909-203253413 (-)
DBA/2J MGP_DBA2J_G0016741
protein coding gene Chr1:180749234-180890044 (-)
FVB/NJ MGP_FVBNJ_G0016737
protein coding gene Chr1:178885286-179022816 (-)
LP/J MGP_LPJ_G0016816
protein coding gene Chr1:190902699-191050868 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016769
protein coding gene Chr1:210062530-210218158 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017337
protein coding gene Chr1:187208959-187348059 (-)
PWK/PhJ MGP_PWKPhJ_G0016031
protein coding gene Chr1:179941680-180074257 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015807
protein coding gene Chr1:186161208-186308562 (-)
WSB/EiJ MGP_WSBEiJ_G0016306
protein coding gene Chr1:187387789-187529284 (-)



Homology
more
  • Human Ortholog
    DISP1, dispatched RND transporter family member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DISP1, dispatched RND transporter family member 1
  • Synonyms
    DISPA
  • Links
    NCBI Gene ID: 84976
    neXtProt AC: NX_Q96F81
    UniProt: Q96F81

  • Chr Location
    1q41; chr1:222815022-223005995 (+)  GRCh38

Human Diseases
less
  • Mutations/Alleles
    2 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    64 phenotypes from 6 alleles in 6 genetic backgrounds
    16 phenotypes from multigenic genotypes
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for targeted and chemically induced mutations exhibit a dorsalized neural tube, impaired heart looping, pericardial edema, large forelimbs, and abnormal head shape.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000030768 Ensembl Gene Model | MGI Sequence Detail 135257 C57BL/6J ±  kb
    transcript ENSMUST00000171366 Ensembl | MGI Sequence Detail 4687 Not Applicable  
    polypeptide ENSMUSP00000126742 Ensembl | MGI Sequence Detail 1521 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 13
      Other 2

      Microarray probesets 4
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 9
      Diseases 1
      Gene Ontology 7
      Phenotypes 16
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:344557 Hall ET, et al., Cytoneme signaling provides essential contributions to mammalian tissue patterning. Cell. 2024 Jan 18;187(2):276-293.e23

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    09/24/2024
    MGI 6.24
    The Jackson Laboratory