About   Help   FAQ
Duxbl1 Gene Detail
Summary
  • Symbol
    Duxbl1
  • Name
    double homeobox B-like 1
  • Synonyms
    1110051B16Rik, Duxbl, Duxl
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916048
    NCBI Gene: 278672
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr14:25979001-25990512 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 15.30 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916048
 protein coding gene Chr14:25979001-25990590 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021078
 protein coding gene Chr14:18928858-18939677 (+)
A/J MGP_AJ_G0021027
 protein coding gene Chr14:18455519-18466459 (+)
AKR/J MGP_AKRJ_G0021004
 protein coding gene Chr14:19106120-19118859 (+)
BALB/cJ MGP_BALBcJ_G0021030
 protein coding gene Chr14:18553121-18563880 (+)
C3H/HeJ MGP_C3HHeJ_G0020814
 protein coding gene Chr14:19327880-19338623 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021463
 protein coding gene Chr14:19952591-19991870 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0020338
 protein coding gene Chr14:18933752-18945027 (+)
CBA/J MGP_CBAJ_G0020780
 protein coding gene Chr14:20459364-20471219 (+)
DBA/2J MGP_DBA2J_G0020903
 protein coding gene Chr14:18529518-18543023 (+)
FVB/NJ MGP_FVBNJ_G0020886
 protein coding gene Chr14:18137139-18149273 (+)
LP/J MGP_LPJ_G0026977
 protein coding gene Chr3:1892488-1903281 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020912
 protein coding gene Chr14:20142439-20153698 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021496
 protein coding gene Chr14:18941393-18954489 (+)
PWK/PhJ MGP_PWKPhJ_G0020087
 protein coding gene Chr14:17885379-17896361 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019910
 protein coding gene Chr14:18733729-18740996 (+)
WSB/EiJ MGP_WSBEiJ_G0020394
 protein coding gene Chr14:18894452-18905872 (+)



Homology
more
  • Human Ortholog
    DUXB, double homeobox B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DUXB, double homeobox B
  • Links
    NCBI Gene ID: 100033411
    UniProt: A0A1W2PPF3

  • Chr Location
    16q23.1; chr16:75693893-75701461 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    818
  • Tissues
    56
  • cDNA Data
    7
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048502 Ensembl Gene Model | MGI Sequence Detail 11512 C57BL/6J ±  kb
transcript ENSMUST00000049793 Ensembl | MGI Sequence Detail 2266 Not Applicable  
polypeptide ENSMUSP00000056056 Ensembl | MGI Sequence Detail 350 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR000047 Helix-turn-helix motif
    IPR001356 Homeobox domain
    IPR009057 Homeobox-like domain superfamily
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 6
References
more
  • Summaries
    All 33
    Developmental Gene Expression 7
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:346215 Vega-Sendino M, et al., The homeobox transcription factor DUXBL controls exit from totipotency. Nat Genet. 2024 Mar 20;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory