Tmem140 Gene Detail

Summary

• Symbol
  Tmem140
• Name
  transmembrane protein 140
• Synonyms
  1110007F12Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1915737
  NCBI Gene: 68487
• Alliance
  gene page
• Transcription Start Sites
  10 TSS

Location &
Maps

• Sequence Map
  Chr6:34840081-34851881 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 6, 15.18 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  425 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1915737	protein coding gene	Chr6:34840081-34851881 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0030563	protein coding gene	Chr6:32969247-32984961 (+)
A/J	MGP_AJ_G0030536	protein coding gene	Chr6:31554862-31566663 (+)
AKR/J	MGP_AKRJ_G0030463	protein coding gene	Chr6:32627262-32640593 (+)
BALB/cJ	MGP_BALBcJ_G0030546	protein coding gene	Chr6:31735238-31747534 (+)
C3H/HeJ	MGP_C3HHeJ_G0030259	protein coding gene	Chr6:32576154-32588829 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0031000	protein coding gene	Chr6:33790396-33803649 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0028212	protein coding gene	Chr6:29647558-29659250 (+)
CAST/EiJ	MGP_CASTEiJ_G0029661	protein coding gene	Chr6:32402510-32414333 (+)
CBA/J	MGP_CBAJ_G0030237	protein coding gene	Chr6:35096017-35114120 (+)
DBA/2J	MGP_DBA2J_G0030381	protein coding gene	Chr6:31433370-31446015 (+)
FVB/NJ	MGP_FVBNJ_G0030335	protein coding gene	Chr6:31225448-31237745 (+)
LP/J	MGP_LPJ_G0030468	protein coding gene	Chr6:33084383-33096171 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0030371	protein coding gene	Chr6:37423981-37436619 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0031030	protein coding gene	Chr6:32501881-32514611 (+)
PWK/PhJ	MGP_PWKPhJ_G0029375	protein coding gene	Chr6:31051403-31063371 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0029211	protein coding gene	Chr6:32186247-32297190 (+)
WSB/EiJ	MGP_WSBEiJ_G0029737	protein coding gene	Chr6:32431828-32444681 (+)

Homology

• Human Ortholog
  TMEM140, transmembrane protein 140

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  TMEM140, transmembrane protein 140
  
• Links
  HGNC:21870

  NCBI Gene ID: 55281

  UniProt: Q9NV12

  
  
• Chr Location
  7q33; chr7:135148072-135166215 (+)  GRCh38

---

• MGI Vertebrate Homology
  Tmem140 stringent orthology
  1 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: TMEM140
• Gene Tree
  Tmem140
  

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  2

Expression

• Assay Results
  706
• cDNA Data
  6

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase tmem140

Sequences &
Gene Models

• All Sequences
  45
• RefSeq
  6
• UniProt
  3
• CCDS
  CCDS19996.1

• Ensembl
  ENSMUSG00000057137 (Evidence)
• NCBI Gene
  68487

Representative Sequences			Length	Strain/Species
genomic	68487	NCBI Gene Model | MGI Sequence Detail	11801	C57BL/6J
transcript	NM_001368365	RefSeq | MGI Sequence Detail	2922	C57BL/6
polypeptide	Q8BGY5	UniProt | EBI | MGI Sequence Detail	185	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000032552 transmembrane protein 140
  (term hierarchy)
• InterPro Domains
  IPR028038 TM140 protein family

Molecular
Reagents

• All nucleic 6

  cDNA 6

  
  

  Microarray probesets 3

References

• Summaries
  All 19

  Gene Ontology 2
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563

TSS for Tmem140:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr55559	Chr6:34840036-34840047 (+)	-39 bp
Tssr55560	Chr6:34840049-34840055 (+)	-29 bp
Tssr55561	Chr6:34840065-34840118 (+)	11 bp
Tssr55562	Chr6:34840153-34840176 (+)	84 bp
Tssr55563	Chr6:34842024-34842030 (+)	1,946 bp
Tssr55564	Chr6:34843284-34843321 (+)	3,222 bp
Tssr55565	Chr6:34843898-34843907 (+)	3,822 bp
Tssr55566	Chr6:34850289-34850300 (+)	10,214 bp
Tssr55567	Chr6:34850310-34850325 (+)	10,237 bp
Tssr55568	Chr6:34850327-34850339 (+)	10,252 bp