About   Help   FAQ
Lrrc28 Gene Detail
Summary
  • Symbol
    Lrrc28
  • Name
    leucine rich repeat containing 28
  • Synonyms
    1300004K21Rik, 2210012C09Rik, 2310058O11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915689
    NCBI Gene: 67867
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:67163158-67295016 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 37.05 cM, cytoband C
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1502 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915689
 protein coding gene Chr7:67163158-67295084 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032359
 protein coding gene Chr7:68769169-68911588 (-)
A/J MGP_AJ_G0032338
 protein coding gene Chr7:67354645-67487054 (-)
AKR/J MGP_AKRJ_G0032274
 protein coding gene Chr7:68776295-68914931 (-)
BALB/cJ MGP_BALBcJ_G0032350
 protein coding gene Chr7:67092208-67222914 (-)
C3H/HeJ MGP_C3HHeJ_G0032063
 protein coding gene Chr7:69466023-69600854 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032842
 protein coding gene Chr7:71725937-71861157 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029849
 protein coding gene Chr7:70214098-70345075 (-)
CAST/EiJ MGP_CASTEiJ_G0031391
 protein coding gene Chr7:60164488-60297942 (-)
CBA/J MGP_CBAJ_G0032029
 protein coding gene Chr7:73960904-74103479 (-)
DBA/2J MGP_DBA2J_G0032184
 protein coding gene Chr7:66074859-66204440 (-)
FVB/NJ MGP_FVBNJ_G0032139
 protein coding gene Chr7:66190221-66320827 (-)
LP/J MGP_LPJ_G0032265
 protein coding gene Chr7:70000800-70133389 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032176
 protein coding gene Chr7:74181742-74321060 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032860
 protein coding gene Chr7:68145344-68278337 (-)
PWK/PhJ MGP_PWKPhJ_G0031111
 protein coding gene Chr7:59123306-59257751 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030952
 protein coding gene Chr7:55185538-55325577 (-)
WSB/EiJ MGP_WSBEiJ_G0031509
 protein coding gene Chr7:68478798-68619310 (-)



Homology
more
  • Human Ortholog
    LRRC28, leucine rich repeat containing 28
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC28, leucine rich repeat containing 28
  • Links
    NCBI Gene ID: 123355
    neXtProt AC: NX_Q86X40
    UniProt: Q86X40

  • Chr Location
    15q26.3; chr15:99251362-99390729 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    47
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030556 Ensembl Gene Model | MGI Sequence Detail 131859 C57BL/6J ±  kb
transcript ENSMUST00000053950 Ensembl | MGI Sequence Detail 2923 Not Applicable  
polypeptide ENSMUSP00000052177 Ensembl | MGI Sequence Detail 367 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 47
    cDNA 47

    Microarray probesets 6
Other
Accession IDs
less
MGI:1915117, MGI:1917638
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Phenotypes 13
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:284228 Ikegami K, et al., Effect of expression alteration in flanking genes on phenotypes of St8sia2-deficient mice. Sci Rep. 2019 Sep 20;9(1):13634
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory