0610010K14Rik MGI Mouse Gene Detail - MGI:1915609

Symbol

0610010K14Rik
Name

RIKEN cDNA 0610010K14 gene
Synonyms

1110020A23Rik

Feature Type

protein coding gene
IDs

MGI:1915609
NCBI Gene: 104457
Alliance

gene page
Transcription Start Sites

10 TSS

Sequence Map

Chr11:70126032-70128740 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 42.99 cM
Mapping Data

2 experiments

SNPs within 2kb

60 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1915609	protein coding gene	Chr11:70126030-70128808 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0018587	protein coding gene	Chr11:70755738-70758454 (-)
A/J	MGP_AJ_G0018555	protein coding gene	Chr11:68067053-68069769 (-)
AKR/J	MGP_AKRJ_G0018524	protein coding gene	Chr11:70097537-70100250 (-)
BALB/cJ	MGP_BALBcJ_G0018527	protein coding gene	Chr11:68389828-68392541 (-)
C3H/HeJ	MGP_C3HHeJ_G0018340	protein coding gene	Chr11:70135899-70138616 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0018978	protein coding gene	Chr11:72853839-72856557 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016624	protein coding gene	Chr11:64985586-64988285 (-)
CAST/EiJ	MGP_CASTEiJ_G0017895	protein coding gene	Chr11:70381520-70384235 (-)
CBA/J	MGP_CBAJ_G0018312	protein coding gene	Chr11:76164197-76166910 (-)
DBA/2J	MGP_DBA2J_G0018422	protein coding gene	Chr11:67642813-67645524 (-)
FVB/NJ	MGP_FVBNJ_G0018412	protein coding gene	Chr11:67298303-67301020 (-)
LP/J	MGP_LPJ_G0018493	protein coding gene	Chr11:71325444-71328149 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0018435	protein coding gene	Chr11:76732360-76735073 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019020	protein coding gene	Chr11:70369333-70372052 (-)
PWK/PhJ	MGP_PWKPhJ_G0017669	protein coding gene	Chr11:68296763-68299474 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0017459	protein coding gene	Chr11:70167221-70169935 (-)
WSB/EiJ	MGP_WSBEiJ_G0017949	protein coding gene	Chr11:70032767-70035486 (-)

Human Ortholog

C17orf49, chromosome 17 open reading frame 49

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

C17orf49, chromosome 17 open reading frame 49
Synonyms

BAP18, HEPIS
Links

HGNC:28737

NCBI Gene ID: 124944

neXtProt AC: NX_Q8IXM2

UniProt: Q8IXM2
Chr Location

17p13.1; chr17:7014495-7017525 (+) GRCh38

MGI Vertebrate Homology

0610010K14Rik stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: C17orf49
Gene Tree

0610010K14Rik

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Phenotype Summary

4 phenotypes from 1 allele in 1 genetic background
12 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

4
Chemically induced (other)

1
Targeted

3
Genomic Mutations

2 involving 0610010K14Rik
Incidental Mutations

CvDC
Find Mice (IMSR)

8 strains or lines available

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All GO Annotations

11
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

937
Tissues

90
cDNA Data

69
Literature Summary

5

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

ZFIN zgc:103508, zgc:92664

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All Sequences

89
RefSeq

18
UniProt

8
CCDS

CCDS24940.1, CCDS48831.1, CCDS48832.1, CCDS48833.1, CCDS48834.1, CCDS48835.1

Ensembl

ENSMUSG00000020831 (Evidence)
NCBI Gene

104457

			Length	Strain/Species	Flank
genomic	ENSMUSG00000020831	Ensembl Gene Model \| MGI Sequence Detail	2709	C57BL/6J	± kb
transcript	ENSMUST00000108576	Ensembl \| MGI Sequence Detail	576	Not Applicable
polypeptide	ENSMUSP00000104216	Ensembl \| MGI Sequence Detail	191	Not Applicable

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UniProt

8 Sequences
InterPro Domains

IPR009057 Homeobox-like domain superfamily

IPR001005 SANT/Myb domain

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All nucleic 70

cDNA 70

Microarray probesets 4

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MGI:1915782, MGI:2144361, MGI:2144443

Summaries

All 40

Developmental Gene Expression 5

Gene Ontology 4

Phenotypes 12
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

TSS for 0610010K14Rik:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr108934	Chr11:70129290-70129301 (-)	-556 bp
Tssr108933	Chr11:70129219-70129246 (-)	-493 bp
Tssr108932	Chr11:70129198-70129214 (-)	-466 bp
Tssr108931	Chr11:70129131-70129148 (-)	-400 bp
Tssr108930	Chr11:70128712-70128745 (-)	11 bp
Tssr108929	Chr11:70128678-70128711 (-)	45 bp
Tssr108928	Chr11:70128587-70128607 (-)	143 bp
Tssr108927	Chr11:70128464-70128477 (-)	269 bp
Tssr108926	Chr11:70128431-70128459 (-)	295 bp
Tssr108925	Chr11:70128396-70128426 (-)	329 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23