About   Help   FAQ
Fam114a1 Gene Detail
Summary
  • Symbol
    Fam114a1
  • Name
    family with sequence similarity 114, member A1
  • Synonyms
    1190001N04Rik, 9130005N14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915553
    NCBI Gene: 68303
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:65127459-65199217 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 33.55 cM, cytoband C3.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    695 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915553
 protein coding gene Chr5:65127414-65199229 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029570
 protein coding gene Chr5:64577602-64656495 (+)
A/J MGP_AJ_G0029538
 protein coding gene Chr5:62182795-62259423 (+)
AKR/J MGP_AKRJ_G0029486
 protein coding gene Chr5:64140289-64220489 (+)
BALB/cJ MGP_BALBcJ_G0029547
 protein coding gene Chr5:62869929-62943875 (+)
C3H/HeJ MGP_C3HHeJ_G0029270
 protein coding gene Chr5:64496233-64572476 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030001
 protein coding gene Chr5:67257699-67339991 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027241
 protein coding gene Chr5:58254424-58325610 (+)
CAST/EiJ MGP_CASTEiJ_G0028678
 protein coding gene Chr5:63591391-63670008 (+)
CBA/J MGP_CBAJ_G0029239
 protein coding gene Chr5:69419010-69512854 (+)
DBA/2J MGP_DBA2J_G0029385
 protein coding gene Chr5:62200778-62274197 (+)
FVB/NJ MGP_FVBNJ_G0029345
 protein coding gene Chr5:61389059-61462382 (+)
LP/J MGP_LPJ_G0029470
 protein coding gene Chr5:65069347-65145304 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029373
 protein coding gene Chr5:72317128-72394667 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030034
 protein coding gene Chr5:63831868-63906615 (+)
PWK/PhJ MGP_PWKPhJ_G0028402
 protein coding gene Chr5:61176633-61251011 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028236
 protein coding gene Chr5:63138768-63213368 (+)
WSB/EiJ MGP_WSBEiJ_G0028758
 protein coding gene Chr5:64028149-64104891 (+)



Homology
more
  • Human Ortholog
    FAM114A1, family with sequence similarity 114 member A1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM114A1, family with sequence similarity 114 member A1
  • Synonyms
    Noxp20
  • Links
    NCBI Gene ID: 92689
    neXtProt AC: NX_Q8IWE2
    UniProt: Q8IWE2

  • Chr Location
    4p14; chr4:38867677-38945739 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    23 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    742
  • Tissues
    2
  • cDNA Data
    53
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68303 NCBI Gene Model | MGI Sequence Detail 71759 C57BL/6J ±  kb
    transcript NM_026667 RefSeq | MGI Sequence Detail 2881 C57BL/6  
    polypeptide Q9D281 UniProt | EBI | MGI Sequence Detail 569 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 53
      cDNA 53

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1916158
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 23
    • Earliest
      J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
    • Latest
      J:327254 Subbaiah KCV, et al., FAM114A1 influences cardiac pathological remodeling by regulating angiotensin II signaling. JCI Insight. 2022 Jul 8;7(13):e152783
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory