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Stt3b Gene Detail
Summary
  • Symbol
    Stt3b
  • Name
    STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
  • Synonyms
    1300006C19Rik, Simp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915542
    NCBI Gene: 68292
  • Alliance
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:115071649-115139489 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 67.71 cM, cytoband F3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    678 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915542
protein coding gene Chr9:115071538-115139536 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035398
protein coding gene Chr9:117742030-117815420 (-)
A/J MGP_AJ_G0035378
protein coding gene Chr9:113399312-113468019 (-)
AKR/J MGP_AKRJ_G0035311
protein coding gene Chr9:116296661-116364905 (-)
BALB/cJ MGP_BALBcJ_G0035374
protein coding gene Chr9:113201166-113268485 (-)
C3H/HeJ MGP_C3HHeJ_G0035082
protein coding gene Chr9:116792263-116864402 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035897
protein coding gene Chr9:120964501-121036914 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032780
protein coding gene Chr9:110688671-110753079 (-)
CAST/EiJ MGP_CASTEiJ_G0034387
protein coding gene Chr9:116662631-116735760 (-)
CBA/J MGP_CBAJ_G0035049
protein coding gene Chr9:125516918-125587643 (-)
DBA/2J MGP_DBA2J_G0035208
protein coding gene Chr9:112882128-112952145 (-)
FVB/NJ MGP_FVBNJ_G0035155
protein coding gene Chr9:111711630-111782615 (-)
LP/J MGP_LPJ_G0035287
protein coding gene Chr9:118063026-118140677 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035196
protein coding gene Chr9:126685979-126758027 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035916
protein coding gene Chr9:116671776-116740329 (-)
PWK/PhJ MGP_PWKPhJ_G0034093
protein coding gene Chr9:113193492-113262199 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033927
protein coding gene Chr9:116742681-116813865 (-)
WSB/EiJ MGP_WSBEiJ_G0034507
protein coding gene Chr9:116556993-116627015 (-)



Homology
more
  • Human Ortholog
    STT3B, STT3 oligosaccharyltransferase complex catalytic subunit B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STT3B, STT3 oligosaccharyltransferase complex catalytic subunit B
  • Synonyms
    CDG1X, SIMP, STT3-B
  • Links
    NCBI Gene ID: 201595
    neXtProt AC: NX_Q8TCJ2
    UniProt: Q8TCJ2

  • Chr Location
    3p23; chr3:31532501-31637622 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human STT3B associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032437 Ensembl Gene Model | MGI Sequence Detail 67841 C57BL/6J ±  kb
    transcript ENSMUST00000035010 Ensembl | MGI Sequence Detail 4221 Not Applicable  
    polypeptide ENSMUSP00000035010 Ensembl | MGI Sequence Detail 823 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 16

      Microarray probesets 4
    References
    more
    • Summaries
      All 36
      Gene Ontology 6
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:319945 Ramirez AS, et al., Cryo-electron microscopy structures of human oligosaccharyltransferase complexes OST-A and OST-B. Science. 2019 Dec 13;366(6471):1372-1375

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    01/24/2023
    MGI 6.22
    The Jackson Laboratory