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Fam111a Gene Detail
Summary
  • Symbol
    Fam111a
  • Name
    family with sequence similarity 111, member A
  • Synonyms
    4632417K18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915508
    NCBI Gene: 107373
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:12550874-12567133 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 8.72 cM, cytoband B
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    461 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915508
 protein coding gene Chr19:12523104-12567133 (+)
129S1/SvImJ ENSMUSG00200045281
 protein coding gene Chr19:9232574-9257743 (+)
A/J ENSMUSG00195044791
 protein coding gene Chr19:9370845-9392452 (+)
AKR/J ENSMUSG00220042718
 protein coding gene Chr19:9342571-9367741 (+)
BALB/cJ ENSMUSG00180048491
 protein coding gene Chr19:9735425-9757038 (+)
C3H/HeJ ENSMUSG00175010327
 protein coding gene Chr19:9073859-9099039 (+)
C57BL/6NJ ENSMUSG00215045745
 protein coding gene Chr19:9143313-9168482 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022757
 protein coding gene Chr19:10029600-10050714 (+)
CAST/EiJ ENSTCUG00005038987
 protein coding gene Chr19:8930437-8952036 (+)
CBA/J ENSMUSG00210049099
 protein coding gene Chr19:9272351-9297529 (+)
DBA/2J ENSMUSG00185052182
 protein coding gene Chr19:9682411-9707589 (+)
FVB/NJ ENSMUSG00205028432
 protein coding gene Chr19:9131451-9153095 (+)
JF1/MsJ ENSUMUG00000054272
 protein coding gene Chr19:9769329-9790970 (+)
LP/J ENSMUSG00230015734
 protein coding gene Chr19:10600236-10625405 (+)
NOD/ShiLtJ ENSMUSG00190037992
 protein coding gene Chr19:9095352-9116963 (+)
NZO/HlLtJ ENSMUSG00225045933
 protein coding gene Chr19:14309248-14334417 (+)
PWK/PhJ ENSLUMG00010003899
 protein coding gene Chr19:9183368-9205025 (+)
SPRET/EiJ ENSMSPG00010044087
 protein coding gene Chr19:9015007-9027660 (+)
WSB/EiJ ENSIUOG00005049890
 protein coding gene Chr19:8784718-8809887 (+)



Homology
more
  • Human Ortholog
    FAM111A, FAM111 trypsin like peptidase A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM111A, FAM111 trypsin like peptidase A
  • Synonyms
    GCLEB, KCS2
  • Links
    NCBI Gene ID: 63901
    UniProt: Q96PZ2

  • Chr Location
    11q12.1; chr11:59142703-59155042 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human FAM111A associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Mice homozygous for a null allele exhibit normal electrolyte homeostasis and bone phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    698
  • Tissues
    10
  • cDNA Data
    71
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 107373 NCBI Gene Model | MGI Sequence Detail 16260 C57BL/6J ±  kb
transcript NM_026640 RefSeq | MGI Sequence Detail 3199 C57BL/6  
polypeptide Q9D2L9 UniProt | EBI | MGI Sequence Detail 613 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 71
    cDNA 71

    Microarray probesets 6
Other
Accession IDs
less
MGI:2147729
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory