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Ciao2a Gene Detail
Summary
  • Symbol
    Ciao2a
  • Name
    cytosolic iron-sulfur assembly component 2A
  • Synonyms
    5730536A07Rik, Fam96a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915500
    NCBI Gene: 68250
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:66033893-66046237 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 35.73 cM, cytoband D
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    76 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915500
 protein coding gene Chr9:66033878-66046250 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034973
 protein coding gene Chr9:65931342-65944538 (+)
A/J MGP_AJ_G0034953
 protein coding gene Chr9:63675988-63688512 (+)
AKR/J MGP_AKRJ_G0034883
 protein coding gene Chr9:65194983-65207042 (+)
BALB/cJ MGP_BALBcJ_G0034946
 protein coding gene Chr9:63389330-63402597 (+)
C3H/HeJ MGP_C3HHeJ_G0034656
 protein coding gene Chr9:65722179-65735271 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035465
 protein coding gene Chr9:67717468-67734710 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032376
 protein coding gene Chr9:63333506-63345850 (+)
CAST/EiJ MGP_CASTEiJ_G0033977
 protein coding gene Chr9:65920775-65933662 (+)
CBA/J MGP_CBAJ_G0034627
 protein coding gene Chr9:70068913-70088913 (+)
DBA/2J MGP_DBA2J_G0034786
 protein coding gene Chr9:63451234-63464388 (+)
FVB/NJ MGP_FVBNJ_G0034728
 protein coding gene Chr9:62793845-62805965 (+)
LP/J MGP_LPJ_G0034869
 protein coding gene Chr9:66182860-66197966 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034770
 protein coding gene Chr9:71316915-71331587 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035487
 protein coding gene Chr9:65302924-65316015 (+)
PWK/PhJ MGP_PWKPhJ_G0033681
 protein coding gene Chr9:63650005-63663289 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033515
 protein coding gene Chr9:65589707-65604718 (+)
WSB/EiJ MGP_WSBEiJ_G0034090
 protein coding gene Chr9:65199653-65212569 (+)



Homology
more
  • Human Ortholog
    CIAO2A, cytosolic iron-sulfur assembly component 2A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CIAO2A, cytosolic iron-sulfur assembly component 2A
  • Synonyms
    CIA2A, FAM96A
  • Links
    NCBI Gene ID: 84191
    neXtProt AC: NX_Q9H5X1
    UniProt: Q9H5X1

  • Chr Location
    15q22.31; chr15:64072565-64093857 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    20
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    4
  • Gene trapped
    13
  • Targeted
    2
  • Genomic Mutations
    1 involving Ciao2a
  • Find Mice (IMSR)
    13 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    728
  • Tissues
    1
  • cDNA Data
    91
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032381 Ensembl Gene Model | MGI Sequence Detail 12345 C57BL/6J ±  kb
transcript ENSMUST00000034945 Ensembl | MGI Sequence Detail 1240 Not Applicable  
polypeptide ENSMUSP00000034945 Ensembl | MGI Sequence Detail 160 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 91
    cDNA 91

    Microarray probesets 5
References
more
  • Summaries
    All 42
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:346175 Liu Z, et al., FAM96A is essential for maintaining organismal energy balance and adipose tissue homeostasis in mice. Free Radic Biol Med. 2022 Nov 1;192:115-129
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory