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Fcor Gene Detail
Summary
  • Symbol
    Fcor
  • Name
    Foxo1 corepressor
  • Synonyms
    2400009B08Rik, FCoR
Location &
Maps
more
  • Sequence Map
    Chr8:3721188-3722362 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 1.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    114 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915484
 protein coding gene Chr8:3721185-3722391 (-)
129S1/SvImJ ENSMUSG00200012034
 protein coding gene Chr8:542218-543389 (-)
A/J ENSMUSG00195010119
 protein coding gene Chr8:946454-947628 (-)
AKR/J ENSMUSG00220010283
 protein coding gene Chr8:672988-674162 (-)
BALB/cJ ENSMUSG00180004029
 protein coding gene Chr8:596939-598113 (-)
C3H/HeJ ENSMUSG00175007732
 protein coding gene Chr8:711544-712718 (-)
C57BL/6NJ ENSMUSG00215005169
 protein coding gene Chr8:625898-627072 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0004100
 antisense lncRNA gene Chr8:539611-540750 (-)
CAST/EiJ ENSTCUG00005020273
 protein coding gene Chr8:683763-684936 (-)
CBA/J ENSMUSG00210010594
 protein coding gene Chr8:589113-590287 (-)
DBA/2J ENSMUSG00185003530
 protein coding gene Chr8:725160-726334 (-)
FVB/NJ ENSMUSG00205005470
 protein coding gene Chr8:658978-660152 (-)
JF1/MsJ ENSUMUG00000021621
 protein coding gene Chr8:678874-680045 (-)
LP/J ENSMUSG00230006302
 protein coding gene Chr8:2894754-2895928 (-)
NOD/ShiLtJ ENSMUSG00190010449
 protein coding gene Chr8:699174-700348 (-)
NZO/HlLtJ ENSMUSG00225016599
 protein coding gene Chr8:10760001-10761175 (-)
PWK/PhJ ENSLUMG00010009604
 protein coding gene Chr8:636126-637301 (-)
SPRET/EiJ ENSMSPG00010015796
 protein coding gene Chr8:609310-610484 (-)
WSB/EiJ ENSIUOG00005004406
 protein coding gene Chr8:633638-634813 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotypes from 3 alleles in 2 genetic backgrounds
    6 phenotypes from multigenic genotypes
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit a lean phenotype with impaired glucose tolerance, insulin resistance, decreased body weight and increased oxygen consumption.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    6
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      32
    • RefSeq
      3
    • UniProt
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000089665 Ensembl Gene Model | MGI Sequence Detail 1175 C57BL/6J ±  kb
    transcript ENSMUST00000159364 Ensembl | MGI Sequence Detail 392 Not Applicable  
    polypeptide ENSMUSP00000146366 Ensembl | MGI Sequence Detail 106 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6

      Microarray probesets 2
    References
    more
    • Summaries
      All 19
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 3
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:306907 Kodani N, et al., FCoR-Foxo1 Axis Regulates alpha-Cell Mass through Repression of Arx Expression. iScience. 2020 Jan 24;23(1):100798
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory