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Fam98b Gene Detail
Summary
  • Symbol
    Fam98b
  • Name
    family with sequence similarity 98, member B
  • Synonyms
    2610510H03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915465
    NCBI Gene: 68215
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:117080220-117102021 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 59.15 cM, cytoband E5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    608 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915465
 protein coding gene Chr2:117080150-117102021 (+)
129S1/SvImJ ENSMUSG00200043861
 protein coding gene Chr2:114015784-114037732 (+)
A/J ENSMUSG00195022152
 protein coding gene Chr2:114057655-114079587 (+)
AKR/J ENSMUSG00220042651
 protein coding gene Chr2:113939432-113961373 (+)
BALB/cJ ENSMUSG00180038166
 protein coding gene Chr2:113862848-113884782 (+)
C3H/HeJ ENSMUSG00175027204
 protein coding gene Chr2:114299666-114321604 (+)
C57BL/6NJ ENSMUSG00215012502
 protein coding gene Chr2:113994766-114016732 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024110
 protein coding gene Chr2:110085295-110110419 (+)
CAST/EiJ ENSTCUG00005016034
 protein coding gene Chr2:113254492-113276532 (+)
CBA/J ENSMUSG00210007469
 protein coding gene Chr2:114140742-114162679 (+)
DBA/2J ENSMUSG00185045819
 protein coding gene Chr2:113859635-113881565 (+)
FVB/NJ ENSMUSG00205041571
 protein coding gene Chr2:113073739-113095687 (+)
JF1/MsJ ENSUMUG00000016289
 protein coding gene Chr2:113729010-113751072 (+)
LP/J ENSMUSG00230015301
 protein coding gene Chr2:115675630-115697595 (+)
NOD/ShiLtJ ENSMUSG00190045012
 protein coding gene Chr2:114054531-114076473 (+)
NZO/HlLtJ ENSMUSG00225004033
 protein coding gene Chr2:123547628-123569567 (+)
PWK/PhJ ENSLUMG00010046500
 protein coding gene Chr2:113657246-113679274 (+)
SPRET/EiJ ENSMSPG00010037771
 protein coding gene Chr2:115972733-115996050 (+)
WSB/EiJ ENSIUOG00005024091
 protein coding gene Chr2:113809856-113831789 (+)



Homology
more
  • Human Ortholog
    TSLIG3B, tRNA splicing ligase complex subunit 3B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TSLIG3B, tRNA splicing ligase complex subunit 3B
  • Synonyms
    FAM98B
  • Links
    NCBI Gene ID: 283742
    UniProt: Q52LJ0

  • Chr Location
    15q14; chr15:38454127-38487710 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    600
  • Tissues
    3
  • cDNA Data
    20
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027349 Ensembl Gene Model | MGI Sequence Detail 21802 C57BL/6J ±  kb
transcript ENSMUST00000028825 Ensembl | MGI Sequence Detail 1861 Not Applicable  
polypeptide ENSMUSP00000028825 Ensembl | MGI Sequence Detail 429 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 2
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:371015 Yang J, et al., Polyglycine-mediated aggregation of FAM98B disrupts tRNA processing in GGC repeat disorders. Science. 2025 Jul 17;389(6757):eado2403
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory