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Rnf227 Gene Detail
Summary
  • Symbol
    Rnf227
  • Name
    ring finger protein 227
  • Synonyms
    2310043C11Rik, A030009H04Rik, Chd3os
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915359
    NCBI Gene: 80515
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:69231287-69233467 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 42.52 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    66 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915359
 protein coding gene Chr11:69231282-69233467 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015181
 unclassified non-coding RNA gene Chr11:69763084-69766568 (+)
A/J MGP_AJ_G0015155
 unclassified non-coding RNA gene Chr11:67139141-67141322 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0015117
 unclassified non-coding RNA gene Chr11:67457901-67460081 (+)
C3H/HeJ MGP_C3HHeJ_G0014941
 unclassified non-coding RNA gene Chr11:69162739-69164919 (+)
C57BL/6NJ MGP_C57BL6NJ_G0015574
 unclassified non-coding RNA gene Chr11:71879321-71881501 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0013317
 unclassified non-coding RNA gene Chr11:64069126-64071323 (+)
CAST/EiJ MGP_CASTEiJ_G0014494
 unclassified non-coding RNA gene Chr11:69403466-69405643 (+)
CBA/J MGP_CBAJ_G0014920
 unclassified non-coding RNA gene Chr11:75093192-75095372 (+)
DBA/2J MGP_DBA2J_G0015013
 unclassified non-coding RNA gene Chr11:66733213-66735395 (+)
FVB/NJ MGP_FVBNJ_G0015025
 unclassified non-coding RNA gene Chr11:66357436-66359617 (+)
LP/J MGP_LPJ_G0015094
 unclassified non-coding RNA gene Chr11:70334598-70338419 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015051
 unclassified non-coding RNA gene Chr11:75710371-75712696 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0015613
 unclassified non-coding RNA gene Chr11:69397374-69399555 (+)
PWK/PhJ MGP_PWKPhJ_G0014286
 unclassified non-coding RNA gene Chr11:67372698-67374879 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014073
 unclassified non-coding RNA gene Chr11:69219793-69221972 (+)
WSB/EiJ MGP_WSBEiJ_G0014597
 unclassified non-coding RNA gene Chr11:69074917-69079506 (+)



Homology
more
  • Human Ortholog
    RNF227, ring finger protein 227
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNF227, ring finger protein 227
  • Synonyms
    LINC02581
  • Links
    NCBI Gene ID: 284023
    UniProt: A6NIN4

  • Chr Location
    17p13.1; chr17:7913324-7916318 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Genomic Mutations
    1 involving Rnf227
  • Find Mice (IMSR)
    2 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    797
  • Tissues
    8
  • cDNA Data
    24
  • Literature Summary
    1
Sequences &
Gene Models
less
  • All Sequences
    43
  • RefSeq
    2
  • UniProt
    4
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043419 Ensembl Gene Model | MGI Sequence Detail 2181 C57BL/6J ±  kb
transcript ENSMUST00000129321 Ensembl | MGI Sequence Detail 2081 Not Applicable  
polypeptide ENSMUSP00000146712 Ensembl | MGI Sequence Detail 190 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 7
Other
Accession IDs
less
MGI:1926026, MGI:1930863, MGI:2142431, MGI:6155714
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/07/2026
MGI 6.24 		The Jackson Laboratory