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Cibar1 Gene Detail
Summary
  • Symbol
    Cibar1
  • Name
    CBY1 interacting BAR domain containing 1
  • Synonyms
    6720467C03Rik, Fam92a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915349
    NCBI Gene: 68099
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:12153409-12172015 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 5.58 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    561 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915349
 protein coding gene Chr4:12153142-12172047 (-)
129S1/SvImJ ENSMUSG00200001051
 protein coding gene Chr4:8796654-8815260 (-)
A/J ENSMUSG00195002797
 protein coding gene Chr4:9248602-9267226 (-)
AKR/J ENSMUSG00220001049
 protein coding gene Chr4:8986516-9005136 (-)
BALB/cJ ENSMUSG00180004405
 protein coding gene Chr4:8758525-8777148 (-)
C3H/HeJ ENSMUSG00175016425
 protein coding gene Chr4:9286540-9305146 (-)
C57BL/6NJ ENSMUSG00215004339
 protein coding gene Chr4:8903310-8921918 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025816
 protein coding gene Chr4:8214336-8230755 (-)
CAST/EiJ ENSTCUG00005023699
 protein coding gene Chr4:8977748-8996429 (-)
CBA/J ENSMUSG00210002516
 protein coding gene Chr4:9024265-9042873 (-)
DBA/2J ENSMUSG00185002502
 protein coding gene Chr4:9134431-9153035 (-)
FVB/NJ ENSMUSG00205002905
 protein coding gene Chr4:8806656-8824943 (-)
JF1/MsJ ENSUMUG00000002103
 protein coding gene Chr4:9234421-9253486 (-)
LP/J ENSMUSG00230001106
 protein coding gene Chr4:12308037-12326651 (-)
NOD/ShiLtJ ENSMUSG00190013167
 protein coding gene Chr4:8876082-8894700 (-)
NZO/HlLtJ ENSMUSG00225007887
 protein coding gene Chr4:16298012-16317053 (-)
PWK/PhJ ENSLUMG00010005772
 protein coding gene Chr4:8702845-8721713 (-)
SPRET/EiJ ENSMSPG00010002657
 protein coding gene Chr4:9092150-9110627 (-)
WSB/EiJ ENSIUOG00005013440
 protein coding gene Chr4:8787480-8805724 (-)



Homology
more
  • Human Ortholog
    CIBAR1, CBY1 interacting BAR domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CIBAR1, CBY1 interacting BAR domain containing 1
  • Synonyms
    BARMR1, FAM92A, FAM92A1, PAPA9
  • Links
    NCBI Gene ID: 137392
    UniProt: A1XBS5

  • Chr Location
    8q22.1; chr8:93698561-93731527 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with Cibar1 mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotypes from 1 allele in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit digit anomalies including metatarsal osteomas and polysyndactyly, tendon calcification, and abnormalities on the deltoid tuberosity of the humerus. Male mice also show aberrations in food intake, decreased leukocyte count, and subfertility associated with decreased testis weight, oligozoospermia, sharply kinked sperm flagella, and mispositioning of the sperm annulus into the principle piece.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    40
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    604
  • Tissues
    3
  • cDNA Data
    44
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000028218 Ensembl Gene Model | MGI Sequence Detail 18607 C57BL/6J ±  kb
    transcript ENSMUST00000108285 Ensembl | MGI Sequence Detail 1639 Not Applicable  
    polypeptide ENSMUSP00000103920 Ensembl | MGI Sequence Detail 355 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • Protein Ontology
      PR:000032451 CBY1-interacting BAR domain-containing protein 1
      (term hierarchy)
    • PDB
      9UHD
    • InterPro Domains
      IPR027267 AH/BAR domain superfamily
      IPR035590 CBY1-interacting BAR domain-containing protein 1/2, BAR domain
      IPR009602 CBY1-interacting BAR domain-containing protein/FAM92
    Molecular
    Reagents
    less
    • All nucleic 44
      cDNA 44
      Antibodies 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:6393847
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 12
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:359301 Kim EN, et al., ciBAR1 loss in mice causes laterality defects, pancreatic degeneration, and altered glucose tolerance. Life Sci Alliance. 2025 Feb;8(2)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory