Yif1a MGI Mouse Gene Detail - MGI:1915340 - Yip1 interacting factor homolog A (S. cerevisiae)

Symbol

Yif1a
Name

Yip1 interacting factor homolog A (S. cerevisiae)
Synonyms

5330422J23Rik, 54TM, Yif1p

Feature Type

protein coding gene
IDs

MGI:1915340
NCBI Gene: 68090
Alliance

genome feature page
Transcription Start Sites

3 TSS

Sequence Map

Chr19:5138566-5142907 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 19, 4.24 cM, cytoband A
Mapping Data

2 experiments

SNPs within 2kb

154 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1915340	protein coding gene	Chr19:5138566-5142909 (+)
129S1/SvImJ	ENSMUSG00200043396	protein coding gene	Chr19:1898937-1903280 (+)
A/J	ENSMUSG00195052525	protein coding gene	Chr19:2294250-2298593 (+)
AKR/J	ENSMUSG00220045232	protein coding gene	Chr19:2067328-2071670 (+)
BALB/cJ	ENSMUSG00180049163	protein coding gene	Chr19:2668974-2673317 (+)
C3H/HeJ	ENSMUSG00175009545	protein coding gene	Chr19:1913691-1918033 (+)
C57BL/6NJ	ENSMUSG00215039582	protein coding gene	Chr19:2137114-2141457 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022534	protein coding gene	Chr19:1843936-1848305 (+)
CAST/EiJ	ENSTCUG00005028230	protein coding gene	Chr19:2057549-2061895 (+)
CBA/J	ENSMUSG00210044782	protein coding gene	Chr19:1917773-1922118 (+)
DBA/2J	ENSMUSG00185038651	protein coding gene	Chr19:2294239-2298583 (+)
FVB/NJ	ENSMUSG00205047315	protein coding gene	Chr19:2297363-2301711 (+)
JF1/MsJ	ENSUMUG00000050328	protein coding gene	Chr19:2277629-2282006 (+)
LP/J	ENSMUSG00230052346	protein coding gene	Chr19:3205880-3210223 (+)
NOD/ShiLtJ	ENSMUSG00190049079	protein coding gene	Chr19:1828741-1833083 (+)
NZO/HlLtJ	ENSMUSG00225025921	protein coding gene	Chr19:6914626-6918969 (+)
PWK/PhJ	ENSLUMG00010007291	protein coding gene	Chr19:2050251-2054627 (+)
SPRET/EiJ	ENSMSPG00010045648	protein coding gene	Chr19:2041356-2045702 (+)
WSB/EiJ	ENSIUOG00005040081	protein coding gene	Chr19:1928979-1933320 (+)

Human Ortholog

YIF1A, Yip1 interacting factor homolog A, membrane trafficking protein

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

YIF1A, Yip1 interacting factor homolog A, membrane trafficking protein
Synonyms

54TM, FinGER7, YIF1, YIF1P
Links

HGNC:16688

NCBI Gene ID: 10897

UniProt: O95070
Chr Location

11q13.2; chr11:66284572-66289184 (-) GRCh38

MGI Vertebrate Homology

Yif1a stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: YIF1A
Gene Tree

Yif1a

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
7 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

3
Endonuclease-mediated

1
Targeted

2
Find Mice (IMSR)

12 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

22
GO References

7

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

602
Tissues

5
cDNA Data

112
Literature Summary

1

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

ZFIN yif1a

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All Sequences

50
RefSeq

2
UniProt

5
CCDS

CCDS29450.1

Ensembl

ENSMUSG00000024875 (Evidence)
NCBI Gene

68090

			Length	Strain/Species	Flank
genomic	68090	NCBI Gene Model \| MGI Sequence Detail	4342	C57BL/6J	± kb
transcript	NM_026553	RefSeq \| MGI Sequence Detail	1493	C57BL/6
polypeptide	Q91XB7	UniProt \| EBI \| MGI Sequence Detail	293	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000017529 protein YIF1A

(term hierarchy)
InterPro Domains

IPR005578 Yif1 family

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All nucleic 113

cDNA 112

Primer pair 1

Microarray probesets 5

Summaries

All 40

Developmental Gene Expression 1

Gene Ontology 7

Phenotypes 7
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Yif1a:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr154389	Chr19:5138562-5138603 (+)	17 bp
Tssr154390	Chr19:5138608-5138619 (+)	48 bp
Tssr154391	Chr19:5138676-5138683 (+)	114 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/01/2026 MGI 6.24