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Lurap1 Gene Detail
Summary
  • Symbol
    Lurap1
  • Name
    leucine rich adaptor protein 1
  • Synonyms
    1520402A15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915325
    NCBI Gene: 68075
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:115993925-116001813 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 53.10 cM, cytoband C7
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915325
 protein coding gene Chr4:115989603-116008535 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028620
 protein coding gene Chr4:116983695-117004810 (-)
A/J MGP_AJ_G0028581
 protein coding gene Chr4:112526592-112546009 (-)
AKR/J MGP_AKRJ_G0028531
 protein coding gene Chr4:114941338-114963369 (-)
BALB/cJ MGP_BALBcJ_G0028602
 protein coding gene Chr4:113157888-113176842 (-)
C3H/HeJ MGP_C3HHeJ_G0028316
 protein coding gene Chr4:116517512-116537051 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029043
 protein coding gene Chr4:121535845-121554604 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026327
 protein coding gene Chr4:106576923-106593456 (-)
CAST/EiJ MGP_CASTEiJ_G0027750
 protein coding gene Chr4:113743060-113765006 (-)
CBA/J MGP_CBAJ_G0028283
 protein coding gene Chr4:124835860-124854556 (-)
DBA/2J MGP_DBA2J_G0028431
 protein coding gene Chr4:113169447-113188238 (-)
FVB/NJ MGP_FVBNJ_G0028399
 protein coding gene Chr4:111667446-111687240 (-)
LP/J MGP_LPJ_G0028533
 protein coding gene Chr4:117200582-117225701 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028426
 protein coding gene Chr4:129833388-129852829 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029080
 protein coding gene Chr4:116101102-116121226 (-)
PWK/PhJ MGP_PWKPhJ_G0027476
 protein coding gene Chr4:109938036-109957406 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027299
 protein coding gene Chr4:112350441-112368950 (-)
WSB/EiJ MGP_WSBEiJ_G0027829
 protein coding gene Chr4:115972727-115993645 (-)



Homology
more
  • Human Ortholog
    LURAP1, leucine rich adaptor protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LURAP1, leucine rich adaptor protein 1
  • Synonyms
    C1orf190, LRAP35a, LRP35A
  • Links
    NCBI Gene ID: 541468
    neXtProt AC: NX_Q96LR2
    UniProt: Q96LR2

  • Chr Location
    1p34.1; chr1:46203334-46221256 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    17
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68075 NCBI Gene Model | MGI Sequence Detail 7889 C57BL/6J ±  kb
    transcript NM_026547 RefSeq | MGI Sequence Detail 1427 C57BL/6  
    polypeptide Q9D6I9 UniProt | EBI | MGI Sequence Detail 239 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 17

      Microarray probesets 2
    References
    more
    • Summaries
      All 37
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:240708 Shiraishi A, et al., DOCK8 Protein Regulates Macrophage Migration through Cdc42 Protein Activation and LRAP35a Protein Interaction. J Biol Chem. 2017 Feb 10;292(6):2191-2202
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory