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Tmem59l Gene Detail
Summary
  • Symbol
    Tmem59l
  • Name
    transmembrane protein 59-like
  • Synonyms
    5330410G16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915187
    NCBI Gene: 67937
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:70936517-70940008 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 34.15 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    88 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915187
 protein coding gene Chr8:70936505-70940008 (-)
129S1/SvImJ ENSMUSG00200029483
 protein coding gene Chr8:65733809-65737302 (-)
A/J ENSMUSG00195013397
 protein coding gene Chr8:66067339-66070831 (-)
AKR/J ENSMUSG00220022421
 protein coding gene Chr8:65979218-65982709 (-)
BALB/cJ ENSMUSG00180023357
 protein coding gene Chr8:65710227-65713721 (-)
C3H/HeJ ENSMUSG00175020686
 protein coding gene Chr8:65990158-65993651 (-)
C57BL/6NJ ENSMUSG00215032476
 protein coding gene Chr8:65669834-65673325 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031146
 protein coding gene Chr8:62695747-62699227 (-)
CAST/EiJ ENSTCUG00005032308
 protein coding gene Chr8:65465385-65468870 (-)
CBA/J ENSMUSG00210032362
 protein coding gene Chr8:65755727-65759220 (-)
DBA/2J ENSMUSG00185012311
 protein coding gene Chr8:71915333-71918826 (-)
FVB/NJ ENSMUSG00205040196
 protein coding gene Chr8:65259941-65263434 (-)
JF1/MsJ ENSUMUG00000032332
 protein coding gene Chr8:74195743-74199234 (-)
LP/J ENSMUSG00230032749
 protein coding gene Chr8:75526893-75530386 (-)
NOD/ShiLtJ ENSMUSG00190022798
 protein coding gene Chr8:65676971-65680462 (-)
NZO/HlLtJ ENSMUSG00225048151
 protein coding gene Chr8:78936043-78939536 (-)
PWK/PhJ ENSLUMG00010033580
 protein coding gene Chr8:65652850-65656339 (-)
SPRET/EiJ ENSMSPG00010037737
 protein coding gene Chr8:67343109-67346601 (-)
WSB/EiJ ENSIUOG00005025594
 protein coding gene Chr8:66546757-66550248 (-)



Homology
more
  • Human Ortholog
    TMEM59L, transmembrane protein 59 like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM59L, transmembrane protein 59 like
  • Synonyms
    BSMAP, C19orf4
  • Links
    NCBI Gene ID: 25789
    UniProt: Q9UK28

  • Chr Location
    19p13.11; chr19:18607430-18621040 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    634
  • Tissues
    25
  • cDNA Data
    34
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035964 Ensembl Gene Model | MGI Sequence Detail 3492 C57BL/6J ±  kb
transcript ENSMUST00000045286 Ensembl | MGI Sequence Detail 1491 Not Applicable  
polypeptide ENSMUSP00000043659 Ensembl | MGI Sequence Detail 337 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 36
    cDNA 35
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 34
    Developmental Gene Expression 6
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory