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Asprv1 Gene Detail
Summary
  • Symbol
    Asprv1
  • Name
    aspartic peptidase, retroviral-like 1
  • Synonyms
    2300003P22Rik, SASP, SASPase, Taps, TPA-induced aspartic proteinase-like
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915105
    NCBI Gene: 67855
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:86605216-86606692 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 37.75 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    110 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915105
protein coding gene Chr6:86605146-86606692 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030979
protein coding gene Chr6:87934967-87936513 (+)
A/J MGP_AJ_G0030945
protein coding gene Chr6:84533078-84534624 (+)
AKR/J MGP_AKRJ_G0030876
protein coding gene Chr6:86981819-86983365 (+)
BALB/cJ MGP_BALBcJ_G0030958
protein coding gene Chr6:84545516-84547062 (+)
C3H/HeJ MGP_C3HHeJ_G0030752
protein coding gene Chr6:97479929-97481475 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031415
protein coding gene Chr6:90315073-90316619 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028599
protein coding gene Chr6:82715723-82717265 (+)
CAST/EiJ MGP_CASTEiJ_G0030067
protein coding gene Chr6:87050453-87052000 (+)
CBA/J MGP_CBAJ_G0030642
protein coding gene Chr6:93866389-93867935 (+)
DBA/2J MGP_DBA2J_G0030798
protein coding gene Chr6:83851842-83853388 (+)
FVB/NJ MGP_FVBNJ_G0030751
protein coding gene Chr6:83035404-83036950 (+)
LP/J MGP_LPJ_G0030875
protein coding gene Chr6:87964601-87966147 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030784
protein coding gene Chr6:97984210-97985756 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031442
protein coding gene Chr6:86819824-86821370 (+)
PWK/PhJ MGP_PWKPhJ_G0029782
protein coding gene Chr6:82792373-82793920 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029610
protein coding gene Chr6:85659145-85660689 (+)
WSB/EiJ MGP_WSBEiJ_G0030148
protein coding gene Chr6:87285632-87287178 (+)



Homology
more
  • Human Ortholog
    ASPRV1, aspartic peptidase retroviral like 1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ASPRV1, aspartic peptidase retroviral like 1
  • Synonyms
    ADLI, MUNO, SASP, SASPase, Taps
  • Links
    NCBI Gene ID: 151516
    neXtProt AC: NX_Q53RT3
    UniProt: Q53RT3

  • Chr Location
    2p13.3; chr2:69932717-70087375 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 images
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted null allele develop fine skin wrinkles at the side of their body without any apparent epidermal differentiation defect.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67855 NCBI Gene Model | MGI Sequence Detail 1477 C57BL/6J ±  kb
transcript NM_026414 RefSeq | MGI Sequence Detail 1477 BALB/c  
polypeptide Q09PK2 UniProt | EBI | MGI Sequence Detail 339 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 59
    cDNA 59

    Microarray probesets 3
Other
Accession IDs
less
MGI:1889382
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:330636 Iwata S, et al., An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain. G3 (Bethesda). 2021;11(8)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory