1110002E22Rik Gene Detail

Summary

• Symbol
  1110002E22Rik
• Name
  RIKEN cDNA 1110002E22 gene

• Feature Type
  protein coding gene
• IDs
  MGI:1915066
  NCBI Gene: 102634333
• Alliance
  gene page
• Transcription Start Sites
  5 TSS

Location &
Maps

• Sequence Map
  Chr3:137770813-137787267 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 3, 64.05 cM
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  203 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1915066	protein coding gene	Chr3:137768010-137787267 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0027923	protein coding gene	Chr3:141108889-141125324 (+)
A/J	MGP_AJ_G0027880	protein coding gene	Chr3:136112385-136128889 (+)
AKR/J	MGP_AKRJ_G0027846	protein coding gene	Chr3:139737446-139753921 (+)
BALB/cJ	MGP_BALBcJ_G0027892	protein coding gene	Chr3:135923237-135939725 (+)
C3H/HeJ	MGP_C3HHeJ_G0027622	protein coding gene	Chr3:140061721-140078212 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0028336	protein coding gene	Chr3:145968034-145984488 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025674	protein coding gene	Chr3:131217473-131233674 (+)
CAST/EiJ	MGP_CASTEiJ_G0027078	protein coding gene	Chr3:139831530-139847945 (+)
CBA/J	MGP_CBAJ_G0027599	protein coding gene	Chr3:150931470-150947979 (+)
DBA/2J	MGP_DBA2J_G0027738	protein coding gene	Chr3:135236915-135253358 (+)
FVB/NJ	MGP_FVBNJ_G0027705	protein coding gene	Chr3:132698669-132715108 (+)
LP/J	MGP_LPJ_G0027848	protein coding gene	Chr3:142507624-142524067 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027737	protein coding gene	Chr3:159035735-159052166 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0028394	protein coding gene	Chr3:139275292-139291727 (+)
PWK/PhJ	MGP_PWKPhJ_G0026802	protein coding gene	Chr3:134989022-135005400 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0026629	protein coding gene	Chr3:137365059-137381524 (+)
WSB/EiJ	MGP_WSBEiJ_G0027157	protein coding gene	Chr3:140104873-140121330 (+)

Homology

• Human Ortholog
  C4orf54, chromosome 4 open reading frame 54

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  C4orf54, chromosome 4 open reading frame 54
  
• Synonyms
  FOPV
• Links
  HGNC:27741

  NCBI Gene ID: 285556

  neXtProt AC: NX_D6RIA3

  UniProt: D6RIA3

  
  
• Chr Location
  4q23; chr4:99636529-99657828 (-)  GRCh38

---

• Alliance of Genome Resources
  1110002E22Rik stringent orthology
  1 human;1 mouse;1 zebrafish
  
• HCOP
  vertebrate homology predictions: C4orf54
• Gene Tree
  1110002E22Rik
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotype references
  

• All Mutations and Alleles
  2
• Chemically induced (other)
  1
• Radiation induced
  1
• Genomic Mutations
  2 involving 1110002E22Rik
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  47 strains or lines available

Expression

• Assay Results
  719
• Tissues
  10
• cDNA Data
  4
• Literature Summary
  2

Images

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Interactions

• 1110002E22Rik interacts with 480 markers (Mir1a-1, Mir1a-2, Mir1b, ...) View All

Sequences &
Gene Models

• All Sequences
  33
• RefSeq
  4
• UniProt
  1
• CCDS
  CCDS89691.1

• Ensembl
  ENSMUSG00000090066 (Evidence)
• NCBI Gene
  102634333

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000090066	Ensembl Gene Model | MGI Sequence Detail	16455	C57BL/6J
transcript	ENSMUST00000163080	Ensembl | MGI Sequence Detail	9741	Not Applicable
polypeptide	ENSMUSP00000123851	Ensembl | MGI Sequence Detail	1786	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000059733 uncharacterized protein C4orf54
  (term hierarchy)
• InterPro Domains
  IPR027838 Domain of unknown function DUF4585

Molecular
Reagents

• All nucleic 4

  cDNA 4

  
  

  Microarray probesets 3

Other
Accession IDs

MGI:2139698, MGI:3780463

References

• Summaries
  All 23

  Developmental Gene Expression 2

  Diseases 1

  Phenotypes 4
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

TSS for 1110002E22Rik:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr31937	Chr3:137770818-137770839 (+)	16 bp
Tssr31938	Chr3:137770904-137770917 (+)	98 bp
Tssr31939	Chr3:137770930-137770958 (+)	131 bp
Tssr31940	Chr3:137772386-137772409 (+)	1,585 bp
Tssr31941	Chr3:137772446-137772465 (+)	1,643 bp