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Pllp Gene Detail
Summary
  • Symbol
    Pllp
  • Name
    plasma membrane proteolipid
  • Synonyms
    0610010I06Rik, plasmolipin, Tm4sf11
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915051
    NCBI Gene: 67801
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:95401523-95422870 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 46.66 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    603 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915051
 protein coding gene Chr8:95401522-95422906 (-)
129S1/SvImJ ENSMUSG00200017288
 protein coding gene Chr8:89766808-89788172 (-)
A/J ENSMUSG00195027414
 protein coding gene Chr8:90119974-90141365 (-)
AKR/J ENSMUSG00220036390
 protein coding gene Chr8:90156507-90177878 (-)
BALB/cJ ENSMUSG00180022602
 protein coding gene Chr8:90003938-90025329 (-)
C3H/HeJ ENSMUSG00175023209
 protein coding gene Chr8:90063191-90084576 (-)
C57BL/6NJ ENSMUSG00215018288
 protein coding gene Chr8:89673730-89695119 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031403
 protein coding gene Chr8:86164951-86192767 (-)
CAST/EiJ ENSTCUG00005016808
 protein coding gene Chr8:89519788-89541144 (-)
CBA/J ENSMUSG00210034602
 protein coding gene Chr8:89997780-90019156 (-)
DBA/2J ENSMUSG00185023700
 protein coding gene Chr8:96106660-96128037 (-)
FVB/NJ ENSMUSG00205011161
 protein coding gene Chr8:89091442-89112824 (-)
JF1/MsJ ENSUMUG00000034727
 protein coding gene Chr8:98458339-98479728 (-)
LP/J ENSMUSG00230029601
 protein coding gene Chr8:99760521-99781888 (-)
NOD/ShiLtJ ENSMUSG00190014881
 protein coding gene Chr8:90129906-90151301 (-)
NZO/HlLtJ ENSMUSG00225010601
 protein coding gene Chr8:103156516-103177884 (-)
PWK/PhJ ENSLUMG00010036988
 protein coding gene Chr8:89831919-89853307 (-)
SPRET/EiJ ENSMSPG00010005990
 protein coding gene Chr8:91851896-91872489 (-)
WSB/EiJ ENSIUOG00005018819
 protein coding gene Chr8:90832440-90853795 (-)



Homology
more
  • Human Ortholog
    PLLP, plasmolipin
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLLP, plasmolipin
  • Synonyms
    PMLP, TM4SF11
  • Links
    NCBI Gene ID: 51090
    UniProt: Q9Y342

  • Chr Location
    16q13; chr16:57248547-57284675 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    609
  • Tissues
    3
  • cDNA Data
    8
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67801 NCBI Gene Model | MGI Sequence Detail 21348 C57BL/6J ±  kb
    transcript NM_026385 RefSeq | MGI Sequence Detail 1889 C57BL/6  
    polypeptide Q9DCU2 UniProt | EBI | MGI Sequence Detail 182 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2142726
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 1
      Gene Ontology 8
      Phenotypes 6
    • Earliest
      J:8958 Moshier JA, et al., Structure and in vitro transcription of a mouse B1 cluster containing a unique B1 dimer. Gene. 1987;58(1):19-27
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory