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Pop1 Gene Detail
Summary
  • Symbol
    Pop1
  • Name
    processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)
  • Synonyms
    4932434G09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914974
    NCBI Gene: 67724
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:34495457-34530799 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 14.34 cM, cytoband B3.3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    883 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914974
 protein coding gene Chr15:34495450-34530799 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021782
 protein coding gene Chr15:32807382-32845740 (+)
A/J MGP_AJ_G0021743
 protein coding gene Chr15:31558255-31592101 (+)
AKR/J MGP_AKRJ_G0021721
 protein coding gene Chr15:32418032-32453147 (+)
BALB/cJ MGP_BALBcJ_G0021749
 protein coding gene Chr15:31568474-31602966 (+)
C3H/HeJ MGP_C3HHeJ_G0021524
 protein coding gene Chr15:32392496-32426321 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022188
 protein coding gene Chr15:34072811-34107103 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019726
 protein coding gene Chr15:29446715-29482075 (+)
CAST/EiJ MGP_CASTEiJ_G0021040
 protein coding gene Chr15:32804322-32838812 (+)
CBA/J MGP_CBAJ_G0021493
 protein coding gene Chr15:35125429-35168205 (+)
DBA/2J MGP_DBA2J_G0021617
 protein coding gene Chr15:31359326-31399695 (+)
FVB/NJ MGP_FVBNJ_G0021595
 protein coding gene Chr15:30817647-30853274 (+)
LP/J MGP_LPJ_G0021686
 protein coding gene Chr15:32703413-32738138 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021620
 protein coding gene Chr15:38133497-38167994 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022211
 protein coding gene Chr15:32589260-32627669 (+)
PWK/PhJ MGP_PWKPhJ_G0020784
 protein coding gene Chr15:31406199-31444927 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020622
 protein coding gene Chr15:32288043-32326666 (+)
WSB/EiJ MGP_WSBEiJ_G0021096
 protein coding gene Chr15:32573365-32604204 (+)



Homology
more
  • Human Ortholog
    POP1, POP1 ribonuclease P/MRP subunit
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    POP1, POP1 ribonuclease P/MRP subunit
  • Synonyms
    ANXD2
  • Links
    NCBI Gene ID: 10940
    UniProt: Q99575

  • Chr Location
    8q22.2; chr8:98117293-98159835 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human POP1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    56
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67724 NCBI Gene Model | MGI Sequence Detail 35343 C57BL/6J ±  kb
transcript NM_152894 RefSeq | MGI Sequence Detail 3393 C57BL/6  
polypeptide NP_690854 RefSeq | MGI Sequence Detail 1045 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR009723 Pop1, N-terminal
    IPR012590 POPLD domain
    IPR039182 Ribonucleases P/MRP protein subunit Pop1
  • GlyGen
    Q8K205 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 56
    cDNA 56

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Phenotypes 16
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/16/2026
MGI 6.24 		The Jackson Laboratory