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Tm7sf3 Gene Detail
Summary
  • Symbol
    Tm7sf3
  • Name
    transmembrane 7 superfamily member 3
  • Synonyms
    2010003B14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914873
    NCBI Gene: 67623
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:146503774-146536103 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 77.70 cM, cytoband G3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    487 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914873
 protein coding gene Chr6:146503774-146544322 (-)
129S1/SvImJ ENSMUSG00200003130
 protein coding gene Chr6:144063558-144095334 (-)
A/J ENSMUSG00195003667
 protein coding gene Chr6:142969913-143001680 (-)
AKR/J ENSMUSG00220029852
 protein coding gene Chr6:141200648-141232895 (-)
BALB/cJ ENSMUSG00180002410
 protein coding gene Chr6:143097093-143128872 (-)
C3H/HeJ ENSMUSG00175002461
 protein coding gene Chr6:143006821-143038881 (-)
C57BL/6NJ ENSMUSG00215003465
 protein coding gene Chr6:143158718-143190960 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029056
 protein coding gene Chr6:144341874-144380921 (-)
CAST/EiJ ENSTCUG00005010871
 protein coding gene Chr6:143798987-143830749 (-)
CBA/J ENSMUSG00210004911
 protein coding gene Chr6:143072050-143104114 (-)
DBA/2J ENSMUSG00185015794
 protein coding gene Chr6:143719669-143751727 (-)
FVB/NJ ENSMUSG00205022259
 protein coding gene Chr6:142051221-142083258 (-)
JF1/MsJ ENSUMUG00000007012
 protein coding gene Chr6:142368895-142401115 (-)
LP/J ENSMUSG00230004071
 protein coding gene Chr6:144816308-144848351 (-)
NOD/ShiLtJ ENSMUSG00190002054
 protein coding gene Chr6:143555844-143587881 (-)
NZO/HlLtJ ENSMUSG00225012661
 protein coding gene Chr6:147704357-147736611 (-)
PWK/PhJ ENSLUMG00010033118
 protein coding gene Chr6:141453855-141485561 (-)
SPRET/EiJ ENSMSPG00010015385
 protein coding gene Chr6:145379844-145411382 (-)
WSB/EiJ ENSIUOG00005004369
 protein coding gene Chr6:143748727-143780532 (-)



Homology
more
  • Human Ortholog
    TM7SF3, transmembrane 7 superfamily member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TM7SF3, transmembrane 7 superfamily member 3
  • Links
    NCBI Gene ID: 51768
    UniProt: Q9NS93

  • Chr Location
    12p11.23; chr12:26971579-27014507 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    692
  • Tissues
    95
  • cDNA Data
    79
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67623 NCBI Gene Model | MGI Sequence Detail 32330 C57BL/6J ±  kb
transcript NM_026281 RefSeq | MGI Sequence Detail 3312 C57BL/6  
polypeptide Q9CRG1 UniProt | EBI | MGI Sequence Detail 565 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 81
    cDNA 79
    Primer pair 1
    Other 1

    Microarray probesets 6
References
more
  • Summaries
    All 44
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:349456 Isaac R, et al., TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis. Cell Metab. 2024 May 7;36(5):1030-1043.e7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory