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Gramd2b Gene Detail
Summary
  • Symbol
    Gramd2b
  • Name
    GRAM domain containing 2B
  • Synonyms
    9030613F08Rik, 9130427A09Rik, Gramd3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914815
    NCBI Gene: 107022
  • Alliance
    genome feature page
  • Transcription Start Sites
    18 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:56533412-56636864 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 30.43 cM, cytoband D2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3220 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914815
 protein coding gene Chr18:56533409-56636864 (+)
129S1/SvImJ ENSMUSG00200032350
 protein coding gene Chr18:53625077-53728678 (+)
A/J ENSMUSG00195004930
 protein coding gene Chr18:53747976-53851564 (+)
AKR/J ENSMUSG00220015761
 protein coding gene Chr18:53738060-53841645 (+)
BALB/cJ ENSMUSG00180011985
 protein coding gene Chr18:54318925-54422510 (+)
C3H/HeJ ENSMUSG00175033004
 protein coding gene Chr18:53938092-54041666 (+)
C57BL/6NJ ENSMUSG00215038282
 protein coding gene Chr18:53261731-53365223 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022284
 protein coding gene Chr18:53217806-53297208 (+)
CAST/EiJ ENSTCUG00005025020
 protein coding gene Chr18:53134249-53240427 (+)
CBA/J ENSMUSG00210030347
 protein coding gene Chr18:53878762-53982334 (+)
DBA/2J ENSMUSG00185015273
 protein coding gene Chr18:53790170-53893748 (+)
FVB/NJ ENSMUSG00205012627
 protein coding gene Chr18:53244316-53347912 (+)
JF1/MsJ ENSUMUG00000024771
 protein coding gene Chr18:53679686-53785491 (+)
LP/J ENSMUSG00230010385
 protein coding gene Chr18:55798590-55902186 (+)
NOD/ShiLtJ ENSMUSG00190025759
 protein coding gene Chr18:53494800-53607055 (+)
NZO/HlLtJ ENSMUSG00225034250
 protein coding gene Chr18:55658909-55765439 (+)
PWK/PhJ ENSLUMG00010008053
 protein coding gene Chr18:53821962-53926168 (+)
SPRET/EiJ ENSMSPG00010017964
 protein coding gene Chr18:54200529-54302352 (+)
WSB/EiJ ENSIUOG00005008976
 protein coding gene Chr18:53419274-53522850 (+)



Homology
more
  • Human Ortholog
    GRAMD2B, GRAM domain containing 2B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GRAMD2B, GRAM domain containing 2B
  • Synonyms
    GRAMD3, NS3TP2
  • Links
    NCBI Gene ID: 65983
    UniProt: Q96HH9

  • Chr Location
    5q23.2; chr5:126360120-126496494 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    99
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 107022 NCBI Gene Model | MGI Sequence Detail 103453 C57BL/6J ±  kb
    transcript NM_001360917 RefSeq | MGI Sequence Detail 2615 C57BL/6  
    polypeptide Q6PEM6 UniProt | EBI | MGI Sequence Detail 445 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 99
      cDNA 99

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1921790, MGI:2147344, MGI:7414080
    References
    more
    • Summaries
      All 35
      Gene Ontology 4
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory