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Fam120b Gene Detail
Summary
  • Symbol
    Fam120b
  • Name
    family with sequence similarity 120, member B
  • Synonyms
    4932442K08Rik, CCPG
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914794
    NCBI Gene: 67544
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:15616464-15653843 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 8.95 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1211 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914794
 protein coding gene Chr17:15616464-15653845 (+)
129S1/SvImJ ENSMUSG00200037728
 protein coding gene Chr17:11224095-11261417 (+)
A/J ENSMUSG00195034385
 protein coding gene Chr17:11981506-12018829 (+)
AKR/J ENSMUSG00220022593
 protein coding gene Chr17:11642746-11680068 (+)
BALB/cJ ENSMUSG00180016576
 protein coding gene Chr17:11221932-11259259 (+)
C3H/HeJ ENSMUSG00175040364
 protein coding gene Chr17:11115532-11152854 (+)
C57BL/6NJ ENSMUSG00215042329
 protein coding gene Chr17:11325345-11362667 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021094
 protein coding gene Chr17:11001869-11041715 (+)
CAST/EiJ ENSTCUG00005022196
 protein coding gene Chr17:11646696-11684402 (+)
CBA/J ENSMUSG00210033851
 protein coding gene Chr17:10959667-10996987 (+)
DBA/2J ENSMUSG00185037782
 protein coding gene Chr17:12950144-12987463 (+)
FVB/NJ ENSMUSG00205017429
 protein coding gene Chr17:11636306-11673623 (+)
JF1/MsJ ENSUMUG00000016194
 protein coding gene Chr17:12520625-12558061 (+)
LP/J ENSMUSG00230023850
 protein coding gene Chr17:14348389-14385708 (+)
NOD/ShiLtJ ENSMUSG00190027118
 protein coding gene Chr17:11382203-11419526 (+)
NZO/HlLtJ ENSMUSG00225046249
 protein coding gene Chr17:16301976-16339294 (+)
PWK/PhJ ENSLUMG00010020114
 protein coding gene Chr17:11225697-11263053 (+)
SPRET/EiJ ENSMSPG00010040319
 protein coding gene Chr17:12529687-12564347 (+)
WSB/EiJ ENSIUOG00005037376
 protein coding gene Chr17:11973336-12010442 (+)



Homology
more
  • Human Ortholog
    FAM120B, family with sequence similarity 120 member B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM120B, family with sequence similarity 120 member B
  • Synonyms
    CCPG, dJ894D12.1, KIAA1838, PGCC1, SAN1
  • Links
    NCBI Gene ID: 84498
    UniProt: Q96EK7

  • Chr Location
    6q27; chr6:170290703-170407067 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
mice homozygous for a null allele exhibit increased DNA damage in cardiomyocytes associated with cardiomyocyte hypoplasia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    679
  • Tissues
    51
  • cDNA Data
    76
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67544 NCBI Gene Model | MGI Sequence Detail 37380 C57BL/6J ±  kb
    transcript NR_033586 RefSeq | MGI Sequence Detail 5831 C57BL/6  
    polypeptide Q6RI63 UniProt | EBI | MGI Sequence Detail 786 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000030837 constitutive coactivator of peroxisome proliferator-activated receptor gamma
      (term hierarchy)
    • InterPro Domains
      IPR026784 Constitutive coactivator of PPAR-gamma
      IPR060110 FAM120A/B/C, helical domain
      IPR029060 PIN-like domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 86
      Genomic 3
      cDNA 83
      Antibodies 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2147037, MGI:2147063
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory