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Pabpc6 Gene Detail
Summary
  • Symbol
    Pabpc6
  • Name
    poly(A) binding protein, cytoplasmic 6
  • Synonyms
    4932702K14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914793
    NCBI Gene: 67543
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:9885426-9888633 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 7.47 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    152 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914793
 protein coding gene Chr17:9885424-9888646 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023139
 protein coding gene Chr17:7214005-7217207 (-)
A/J MGP_AJ_G0023107
 protein coding gene Chr17:7164545-7167752 (-)
AKR/J MGP_AKRJ_G0023071
 protein coding gene Chr17:6895141-6898348 (-)
BALB/cJ MGP_BALBcJ_G0023107
 protein coding gene Chr17:6960984-6964191 (-)
C3H/HeJ MGP_C3HHeJ_G0022870
 protein coding gene Chr17:7178945-7182152 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023550
 protein coding gene Chr17:7528425-7531632 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021058
 protein coding gene Chr17:7235297-7238498 (+)
CAST/EiJ MGP_CASTEiJ_G0022384
 protein coding gene Chr17:7173784-7176986 (-)
CBA/J MGP_CBAJ_G0022842
 protein coding gene Chr17:7818697-7821904 (-)
DBA/2J MGP_DBA2J_G0022975
 protein coding gene Chr17:6811479-6814686 (-)
FVB/NJ MGP_FVBNJ_G0022945
 protein coding gene Chr17:6760575-6763782 (-)
LP/J MGP_LPJ_G0023047
 protein coding gene Chr17:7029977-7033184 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022964
 protein coding gene Chr17:7462447-7465649 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023576
 protein coding gene Chr17:7201805-7205012 (-)
PWK/PhJ MGP_PWKPhJ_G0022132
 protein coding gene Chr17:6482811-6486002 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021962
 protein coding gene Chr17:6532716-6535920 (-)
WSB/EiJ MGP_WSBEiJ_G0022441
 protein coding gene Chr17:7486871-7490078 (-)



Homology
more
  • Human Ortholog
    PABPC1, poly(A) binding protein cytoplasmic 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PABPC1, poly(A) binding protein cytoplasmic 1
  • Synonyms
    PAB1, PABP, PABP1, PABPC2, PABPL1
  • Links
    NCBI Gene ID: 26986
    UniProt: P11940

  • Chr Location
    8q22.3; chr8:100685816-100722809 (-)  GRCh38
  • Human Ortholog
    PABPC3, poly(A) binding protein cytoplasmic 3
  • Synonyms
    PABP3, PABPL3, tPABP
  • Links
    NCBI Gene ID: 5042
    UniProt: Q9H361

  • Chr Location
    13q12.13; chr13:25096136-25099254 (+)  GRCh38
Human Diseases
less
  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    385 phenotype references
Homozygous null mice exhibit no overt abnormalities, with normal male and female fertility.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    983
  • Tissues
    78
  • cDNA Data
    19
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67543 NCBI Gene Model | MGI Sequence Detail 3208 C57BL/6J ±  kb
transcript NM_001163836 RefSeq | MGI Sequence Detail 3208 C57BL/6  
polypeptide NP_001157308 RefSeq | MGI Sequence Detail 643 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    IPR036053 PABC (PABP) domain
    IPR034364 PABP, RNA recognition motif 1
    IPR045305 PABP, RNA recognition motif 2
    IPR006515 Polyadenylate binding protein, human types 1, 2, 3, 4
    IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein
    IPR035979 RNA-binding domain superfamily
    IPR000504 RNA recognition motif domain
    IPR003954 RNA recognition motif domain, eukaryote
  • GlyGen
    Q9D4E6 2 sites, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 20
    cDNA 19
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:2146850
References
more
  • Summaries
    All 403
    Developmental Gene Expression 3
    Diseases 6
    Phenotypes 385
  • Earliest
    J:7073 Washburn LL, et al., Sex reversal in XY mice caused by dominant mutation on chromosome 17. Nature. 1983 May 26;303(5915):338-40
  • Latest
    J:388187 Reineke LC, et al., Harnessing viral strategies to reverse cognitive dysfunction through the integrated stress response. Science. 2026 Apr 2;392(6793):eaea8782
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/09/2026
MGI 6.24 		The Jackson Laboratory