Spmip5 MGI Mouse Gene Detail - MGI:1914757 - sperm microtubule inner protein 5

Symbol

Spmip5
Name

sperm microtubule inner protein 5
Synonyms

1700019N19Rik

Feature Type

protein coding gene
IDs

MGI:1914757
NCBI Gene: 67507
Alliance

gene page
Transcription Start Sites

7 TSS

Sequence Map

Chr19:58774233-58782846 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 19, 54.51 cM, cytoband D3
Mapping Data

2 experiments

SNPs within 2kb

281 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914757	protein coding gene	Chr19:58774233-58782893 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0025281	protein coding gene	Chr19:59274278-59282863 (-)
A/J	MGP_AJ_G0025257	protein coding gene	Chr19:56375457-56384185 (-)
AKR/J	MGP_AKRJ_G0025226	protein coding gene	Chr19:58134999-58145313 (-)
BALB/cJ	MGP_BALBcJ_G0025252	protein coding gene	Chr19:56440413-56449102 (-)
C3H/HeJ	MGP_C3HHeJ_G0025012	protein coding gene	Chr19:58387145-58395898 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0025695	protein coding gene	Chr19:60705956-60714606 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0023107	protein coding gene	Chr19:55248345-55257126 (-)
CAST/EiJ	MGP_CASTEiJ_G0024477	protein coding gene	Chr19:58461812-58470377 (-)
CBA/J	MGP_CBAJ_G0024992	protein coding gene	Chr19:63669303-63679684 (-)
DBA/2J	MGP_DBA2J_G0025124	protein coding gene	Chr19:56118285-56127067 (-)
FVB/NJ	MGP_FVBNJ_G0025085	protein coding gene	Chr19:55855391-55864303 (-)
LP/J	MGP_LPJ_G0025210	protein coding gene	Chr19:59138874-59149880 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0025118	protein coding gene	Chr19:62911433-62920075 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025753	protein coding gene	Chr19:58365435-58374070 (-)
PWK/PhJ	MGP_PWKPhJ_G0024225	protein coding gene	Chr19:56123177-56132257 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0024028	protein coding gene	Chr19:57031834-57040918 (-)
WSB/EiJ	MGP_WSBEiJ_G0024547	protein coding gene	Chr19:58486292-58495724 (-)

Human Ortholog

SPMIP5, sperm microtubule inner protein 5

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SPMIP5, sperm microtubule inner protein 5
Synonyms

C10orf82
Links

HGNC:28500

NCBI Gene ID: 143379

UniProt: Q8WW14
Chr Location

10q25.3; chr10:116662211-116670282 (-) GRCh38

MGI Vertebrate Homology

Spmip5 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: SPMIP5
Gene Tree

Spmip5

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
3 phenotype references

All Mutations and Alleles

3
Endonuclease-mediated

1
Targeted

2
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

14 strains or lines available

Male mice homozygous for a mutation are viable and show normal fertility.

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All GO Annotations

1
GO References

1

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

25

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

36
RefSeq

6
UniProt

2
CCDS

CCDS38031.1, CCDS89423.1

Ensembl

ENSMUSG00000026931 (Evidence)
NCBI Gene

67507

			Length	Strain/Species	Flank
genomic	67507	NCBI Gene Model \| MGI Sequence Detail	8614	C57BL/6J	± kb
transcript	NM_001368688	RefSeq \| MGI Sequence Detail	1187	C57BL/6
polypeptide	Q9CQT6	UniProt \| EBI \| MGI Sequence Detail	229	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000059983 sperm-associated microtubule inner protein 5

(term hierarchy)
PDB

8IYJ
InterPro Domains

IPR043246 Sperm-associated microtubule inner protein 5

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All nucleic 25

cDNA 25

Microarray probesets 2

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MGI:7470726

Summaries

All 22

Gene Ontology 1

Phenotypes 3
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:338030 Zhou L, et al., Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility. Cell. 2023 Jun 22;186(13):2897-2910.e19

TSS for Spmip5:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr159980	Chr19:58782868-58782887 (-)	-32 bp
Tssr159979	Chr19:58782832-58782860 (-)	0 bp
Tssr159978	Chr19:58781732-58781739 (-)	1,110 bp
Tssr159977	Chr19:58781709-58781730 (-)	1,126 bp
Tssr159976	Chr19:58781700-58781708 (-)	1,142 bp
Tssr159975	Chr19:58781249-58781264 (-)	1,589 bp
Tssr159974	Chr19:58781226-58781244 (-)	1,611 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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