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Cwc25 Gene Detail
Summary
  • Symbol
    Cwc25
  • Name
    CWC25 spliceosome-associated protein
  • Synonyms
    1300013D05Rik, Ccdc49, R75228
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914730
    NCBI Gene: 67480
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:97636307-97657382 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 61.09 cM, cytoband D
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    134 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914730
 protein coding gene Chr11:97636296-97657439 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019039
 protein coding gene Chr11:100210200-100236207 (-)
A/J MGP_AJ_G0019007
 protein coding gene Chr11:96068610-96092797 (-)
AKR/J MGP_AKRJ_G0018977
 protein coding gene Chr11:99052670-99073778 (-)
BALB/cJ MGP_BALBcJ_G0018980
 protein coding gene Chr11:96569730-96589843 (-)
C3H/HeJ MGP_C3HHeJ_G0018794
 protein coding gene Chr11:99176972-99198545 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019433
 protein coding gene Chr11:103298449-103324990 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017064
 protein coding gene Chr11:93526521-93549066 (-)
CAST/EiJ MGP_CASTEiJ_G0018348
 protein coding gene Chr11:100038777-100064644 (-)
CBA/J MGP_CBAJ_G0018765
 protein coding gene Chr11:107564287-107588483 (-)
DBA/2J MGP_DBA2J_G0018873
 protein coding gene Chr11:95619659-95640699 (-)
FVB/NJ MGP_FVBNJ_G0018862
 protein coding gene Chr11:95116192-95139998 (-)
LP/J MGP_LPJ_G0018943
 protein coding gene Chr11:100712465-100735247 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018889
 protein coding gene Chr11:107402601-107425837 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019473
 protein coding gene Chr11:99360083-99382417 (-)
PWK/PhJ MGP_PWKPhJ_G0018120
 protein coding gene Chr11:96606704-96628628 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017910
 protein coding gene Chr11:99074969-99096950 (-)
WSB/EiJ MGP_WSBEiJ_G0018398
 protein coding gene Chr11:99260237-99282131 (-)



Homology
more
  • Human Ortholog
    CWC25, CWC25 spliceosome associated protein homolog
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CWC25, CWC25 spliceosome associated protein homolog
  • Synonyms
    CCDC49
  • Links
    NCBI Gene ID: 54883
    neXtProt AC: NX_Q9NXE8
    UniProt: Q9NXE8

  • Chr Location
    17q12; chr17:38800441-38825355 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    11
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000018541 Ensembl Gene Model | MGI Sequence Detail 21076 C57BL/6J ±  kb
transcript ENSMUST00000018685 Ensembl | MGI Sequence Detail 3105 Not Applicable  
polypeptide ENSMUSP00000018685 Ensembl | MGI Sequence Detail 416 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 5
Other
Accession IDs
less
MGI:2144706, MGI:3035092
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory