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Nvl Gene Detail
Summary
  • Symbol
    Nvl
  • Name
    nuclear VCP-like
  • Synonyms
    1200009I24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914709
    NCBI Gene: 67459
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:180914703-180971769 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 84.53 cM, cytoband H4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    479 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914709
protein coding gene Chr1:180914703-180974557 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016882
protein coding gene Chr1:187581239-187643896 (-)
A/J MGP_AJ_G0016861
protein coding gene Chr1:179987004-180050923 (-)
AKR/J MGP_AKRJ_G0016827
protein coding gene Chr1:185328166-185389205 (-)
BALB/cJ MGP_BALBcJ_G0016819
protein coding gene Chr1:180621478-180682573 (-)
C3H/HeJ MGP_C3HHeJ_G0016644
protein coding gene Chr1:186116016-186175739 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017282
protein coding gene Chr1:193672331-193733224 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014989
protein coding gene Chr1:170970207-171029392 (-)
CAST/EiJ MGP_CASTEiJ_G0016225
protein coding gene Chr1:185458495-185519659 (-)
CBA/J MGP_CBAJ_G0016618
protein coding gene Chr1:200800698-200871653 (-)
DBA/2J MGP_DBA2J_G0016724
protein coding gene Chr1:178814153-178871920 (-)
FVB/NJ MGP_FVBNJ_G0016720
protein coding gene Chr1:176917471-176975828 (-)
LP/J MGP_LPJ_G0016798
protein coding gene Chr1:188829842-188890863 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016751
protein coding gene Chr1:207967547-208032066 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017319
protein coding gene Chr1:185109463-185170837 (-)
PWK/PhJ MGP_PWKPhJ_G0016013
protein coding gene Chr1:177935737-177994143 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015789
protein coding gene Chr1:184079701-184146162 (-)
WSB/EiJ MGP_WSBEiJ_G0016288
protein coding gene Chr1:185318576-185379972 (-)



Homology
more
  • Human Ortholog
    NVL, nuclear VCP like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NVL, nuclear VCP like
  • Synonyms
    NVL2
  • Links
    NCBI Gene ID: 4931
    neXtProt AC: NX_O15381
    UniProt: O15381

  • Chr Location
    1q42.11; chr1:224227334-224330189 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026516 Ensembl Gene Model | MGI Sequence Detail 57067 C57BL/6J ±  kb
transcript ENSMUST00000027797 Ensembl | MGI Sequence Detail 9392 Not Applicable  
polypeptide ENSMUSP00000027797 Ensembl | MGI Sequence Detail 855 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 18
    Other 1

    Microarray probesets 7
References
more
  • Summaries
    All 31
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory