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Qpctl Gene Detail
Summary
  • Symbol
    Qpctl
  • Name
    glutaminyl-peptide cyclotransferase-like
  • Synonyms
    1810019P04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914619
    NCBI Gene: 67369
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:18874142-18883121 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 9.46 cM, cytoband A2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    85 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914619
 protein coding gene Chr7:18873627-18883216 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031761
 protein coding gene Chr7:17096374-17110598 (-)
A/J MGP_AJ_G0031737
 protein coding gene Chr7:16781614-16791206 (-)
AKR/J MGP_AKRJ_G0031663
 protein coding gene Chr7:17238592-17248192 (-)
BALB/cJ MGP_BALBcJ_G0031742
 protein coding gene Chr7:16973719-16983260 (-)
C3H/HeJ MGP_C3HHeJ_G0031464
 protein coding gene Chr7:17501644-17512406 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032208
 protein coding gene Chr7:17985011-17998142 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029274
 protein coding gene Chr7:18426665-18436495 (-)
CAST/EiJ MGP_CASTEiJ_G0030807
 protein coding gene Chr7:13899941-13909728 (-)
CBA/J MGP_CBAJ_G0031426
 protein coding gene Chr7:18638699-18651882 (-)
DBA/2J MGP_DBA2J_G0031581
 protein coding gene Chr7:16716675-16726216 (-)
FVB/NJ MGP_FVBNJ_G0031533
 protein coding gene Chr7:16580633-16590138 (-)
LP/J MGP_LPJ_G0031664
 protein coding gene Chr7:17441161-17451527 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031569
 protein coding gene Chr7:18497905-18508016 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032236
 protein coding gene Chr7:16847423-16858160 (-)
PWK/PhJ MGP_PWKPhJ_G0030531
 protein coding gene Chr7:13805096-13814878 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030358
 protein coding gene Chr7:11533382-11545027 (-)
WSB/EiJ MGP_WSBEiJ_G0030907
 protein coding gene Chr7:17053909-17064683 (-)



Homology
more
  • Human Ortholog
    QPCTL, glutaminyl-peptide cyclotransferase like
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    QPCTL, glutaminyl-peptide cyclotransferase like
  • Synonyms
    gQC
  • Links
    NCBI Gene ID: 54814
    neXtProt AC: NX_Q9NXS2
    UniProt: Q9NXS2

  • Chr Location
    19q13.32; chr19:45692403-45703989 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67369 NCBI Gene Model | MGI Sequence Detail 8980 C57BL/6J ±  kb
transcript NM_026111 RefSeq | MGI Sequence Detail 2100 C57BL/6  
polypeptide Q8BH73 UniProt | EBI | MGI Sequence Detail 383 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 5
Other
Accession IDs
less
MGI:2142285
References
more
  • Summaries
    All 32
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:334287 Schloesser D, et al., Senescent cells suppress macrophage-mediated corpse removal via upregulation of the CD47-QPCT/L axis. J Cell Biol. 2023 Feb 6;222(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory