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Adissp Gene Detail
Summary
  • Symbol
    Adissp
  • Name
    adipose secreted signaling protein
  • Synonyms
    1700037H04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914576
    NCBI Gene: 67326
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:130988244-131002001 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 63.28 cM, cytoband F3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    632 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914576
 protein coding gene Chr2:130988235-131002001 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026523
 protein coding gene Chr2:134657452-134672851 (-)
A/J MGP_AJ_G0026487
 protein coding gene Chr2:129192827-129206568 (-)
AKR/J MGP_AKRJ_G0026462
 protein coding gene Chr2:132926111-132939874 (-)
BALB/cJ MGP_BALBcJ_G0026499
 protein coding gene Chr2:129578845-129592936 (-)
C3H/HeJ MGP_C3HHeJ_G0026242
 protein coding gene Chr2:133359837-133374141 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026944
 protein coding gene Chr2:138794904-138809296 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024321
 protein coding gene Chr2:123936988-123950666 (-)
CAST/EiJ MGP_CASTEiJ_G0025703
 protein coding gene Chr2:133643461-133657211 (-)
CBA/J MGP_CBAJ_G0026222
 protein coding gene Chr2:143961491-143978541 (-)
DBA/2J MGP_DBA2J_G0026356
 protein coding gene Chr2:128583048-128597041 (-)
FVB/NJ MGP_FVBNJ_G0026320
 protein coding gene Chr2:127211665-127226512 (-)
LP/J MGP_LPJ_G0026461
 protein coding gene Chr2:134887632-134902229 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026340
 protein coding gene Chr2:147778571-147794320 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026999
 protein coding gene Chr2:132881976-132895765 (-)
PWK/PhJ MGP_PWKPhJ_G0025439
 protein coding gene Chr2:128152404-128166428 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025241
 protein coding gene Chr2:132033399-132047187 (-)
WSB/EiJ MGP_WSBEiJ_G0025777
 protein coding gene Chr2:133804162-133817879 (-)



Homology
more
  • Human Ortholog
    ADISSP, adipose secreted signaling protein
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ADISSP, adipose secreted signaling protein
  • Synonyms
    C20orf27
  • Links
    NCBI Gene ID: 54976
    UniProt: Q9GZN8

  • Chr Location
    20p13; chr20:3753508-3768388 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    761
  • Tissues
    28
  • cDNA Data
    74
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027327 Ensembl Gene Model | MGI Sequence Detail 13758 C57BL/6J ±  kb
    transcript ENSMUST00000028800 Ensembl | MGI Sequence Detail 832 Not Applicable  
    polypeptide ENSMUSP00000028800 Ensembl | MGI Sequence Detail 177 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 74
      cDNA 74

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:7414175
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 14
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory