Bmerb1 MGI Mouse Gene Detail - MGI:1914504

Symbol

Bmerb1
Name

bMERB domain containing 1
Synonyms

2900011O08Rik, MINP

Feature Type

protein coding gene
IDs

MGI:1914504
NCBI Gene: 67254
Alliance

genome feature page
Transcription Start Sites

2 TSS

Sequence Map

Chr16:13804468-13919364 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 16, 9.66 cM
Mapping Data

1 experiment

SNPs within 2kb

3385 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914504	protein coding gene	Chr16:13802975-13922916 (+)
129S1/SvImJ	ENSMUSG00200041886	protein coding gene	Chr16:10787279-10902183 (+)
A/J	ENSMUSG00195032891	protein coding gene	Chr16:10352266-10467153 (+)
AKR/J	ENSMUSG00220044033	protein coding gene	Chr16:10649151-10764039 (+)
BALB/cJ	ENSMUSG00180037343	protein coding gene	Chr16:10594658-10705093 (+)
C3H/HeJ	ENSMUSG00175043432	protein coding gene	Chr16:10760673-10880348 (+)
C57BL/6NJ	ENSMUSG00215024963	protein coding gene	Chr16:10469438-10584346 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020475	protein coding gene	Chr16:10475728-10598410 (+)
CAST/EiJ	ENSTCUG00005043304	protein coding gene	Chr16:10644320-10758548 (+)
CBA/J	ENSMUSG00210037340	protein coding gene	Chr16:10777640-10897328 (+)
DBA/2J	ENSMUSG00185031550	protein coding gene	Chr16:10723160-10842841 (+)
FVB/NJ	ENSMUSG00205031688	protein coding gene	Chr16:10709273-10824166 (+)
JF1/MsJ	ENSUMUG00000039897	protein coding gene	Chr16:10817468-10932922 (+)
LP/J	ENSMUSG00230043267	protein coding gene	Chr16:13282795-13397679 (+)
NOD/ShiLtJ	ENSMUSG00190039870	protein coding gene	Chr16:10844162-10959057 (+)
NZO/HlLtJ	ENSMUSG00225032104	protein coding gene	Chr16:16528047-16642927 (+)
PWK/PhJ	ENSLUMG00010044869	protein coding gene	Chr16:10681129-10796366 (+)
SPRET/EiJ	ENSMSPG00010042864	protein coding gene	Chr16:10668340-10784598 (+)
WSB/EiJ	ENSIUOG00005034375	protein coding gene	Chr16:10806037-10919256 (+)

Human Ortholog

BMERB1, bMERB domain containing 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

BMERB1, bMERB domain containing 1
Synonyms

C16orf45, MINP
Links

HGNC:19213

NCBI Gene ID: 89927

UniProt: Q96MC5
Chr Location

16p13.11; chr16:15434475-15625028 (+) GRCh38

MGI Vertebrate Homology

Bmerb1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: BMERB1
Gene Tree

Bmerb1

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Phenotype Summary

4 phenotypes from 1 allele in 1 genetic background
9 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

64
Endonuclease-mediated

1
Gene trapped

63
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

85 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

6
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

981
Tissues

65
cDNA Data

50
Literature Summary

2

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase bmerb1

ZFIN bmerb1

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All Sequences

46
RefSeq

6
UniProt

3
CCDS

CCDS27971.1

Ensembl

ENSMUSG00000044117 (Evidence)
NCBI Gene

67254

			Length	Strain/Species	Flank
genomic	ENSMUSG00000044117	Ensembl Gene Model \| MGI Sequence Detail	114897	C57BL/6J	± kb
transcript	ENSMUST00000056521	Ensembl \| MGI Sequence Detail	2394	Not Applicable
polypeptide	ENSMUSP00000062758	Ensembl \| MGI Sequence Detail	203	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000060023 bMERB domain-containing protein 1

(term hierarchy)
InterPro Domains

IPR022735 bMERB domain

IPR040127 BMERB domain-containing protein 1

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All nucleic 51

cDNA 50

Primer pair 1

Antibodies 1

Microarray probesets 3

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MGI:6285791

Summaries

All 32

Developmental Gene Expression 2

Gene Ontology 3

Phenotypes 9
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Bmerb1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr137173	Chr16:13804460-13804529 (+)	27 bp
Tssr137174	Chr16:13917899-13917910 (+)	113,437 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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