Acbd4 MGI Mouse Gene Detail - MGI:1914381 - acyl-Coenzyme A binding domain containing 4

Symbol

Acbd4
Name

acyl-Coenzyme A binding domain containing 4
Synonyms

2010009P05Rik, 2010015A21Rik

Feature Type

protein coding gene
IDs

MGI:1914381
NCBI Gene: 67131
Alliance

gene page
Transcription Start Sites

8 TSS

Sequence Map

Chr11:102992524-103003026 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 66.71 cM, cytoband D
Mapping Data

3 experiments

SNPs within 2kb

41 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914381	protein coding gene	Chr11:102992508-103005229 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0019255	protein coding gene	Chr11:106137968-106148491 (+)
A/J	MGP_AJ_G0019223	protein coding gene	Chr11:101644223-101654729 (+)
AKR/J	MGP_AKRJ_G0019192	protein coding gene	Chr11:104778807-104789323 (+)
BALB/cJ	MGP_BALBcJ_G0019197	protein coding gene	Chr11:102115500-102125967 (+)
C3H/HeJ	MGP_C3HHeJ_G0019006	protein coding gene	Chr11:105004303-105014826 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0019646	protein coding gene	Chr11:109448328-109461752 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017272	protein coding gene	Chr11:99060547-99074252 (+)
CAST/EiJ	MGP_CASTEiJ_G0018560	protein coding gene	Chr11:106014086-106028381 (+)
CBA/J	MGP_CBAJ_G0018975	protein coding gene	Chr11:113996618-114008735 (+)
DBA/2J	MGP_DBA2J_G0019087	protein coding gene	Chr11:101155444-101166166 (+)
FVB/NJ	MGP_FVBNJ_G0019077	protein coding gene	Chr11:100697698-100708222 (+)
LP/J	MGP_LPJ_G0019156	protein coding gene	Chr11:106658448-106669729 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019108	protein coding gene	Chr11:113385320-113397774 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019684	protein coding gene	Chr11:105163917-105175679 (+)
PWK/PhJ	MGP_PWKPhJ_G0018323	protein coding gene	Chr11:102224063-102234751 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0018115	protein coding gene	Chr11:104919147-104929809 (+)
WSB/EiJ	MGP_WSBEiJ_G0018609	protein coding gene	Chr11:105161731-105172949 (+)

Human Ortholog

ACBD4, acyl-CoA binding domain containing 4

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ACBD4, acyl-CoA binding domain containing 4
Synonyms

HMFT0700
Links

HGNC:23337

NCBI Gene ID: 79777

neXtProt AC: NX_Q8NC06

UniProt: Q8NC06
Chr Location

17q21.31; chr17:45131597-45144181 (+) GRCh38

MGI Vertebrate Homology

Acbd4 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: ACBD4
Gene Tree

Acbd4

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Phenotype Summary

9 phenotype references

All Mutations and Alleles

14
Gene trapped

12
Targeted

2
Genomic Mutations

1 involving Acbd4
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

11 strains or lines available

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All GO Annotations

3
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

740
Tissues

2
cDNA Data

9
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase acbd4

ZFIN acbd4

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All Sequences

78
RefSeq

3
UniProt

12
CCDS

CCDS36347.1

Ensembl

ENSMUSG00000056938 (Evidence)
NCBI Gene

67131

			Length	Strain/Species	Flank
genomic	67131	NCBI Gene Model \| MGI Sequence Detail	10503	C57BL/6J	± kb
transcript	NM_025988	RefSeq \| MGI Sequence Detail	2072	C57BL/6
polypeptide	NP_080264	RefSeq \| MGI Sequence Detail	329	C57BL/6

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UniProt

12 Sequences
InterPro Domains

IPR000582 Acyl-CoA-binding protein, ACBP

IPR022408 Acyl-CoA-binding protein, ACBP, conserved site

IPR035984 Acyl-CoA binding protein superfamily

IPR014352 FERM/acyl-CoA-binding protein superfamily

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All nucleic 9

cDNA 9

Microarray probesets 5

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MGI:1917518, MGI:2144300

Summaries

All 30

Developmental Gene Expression 1

Gene Ontology 1

Phenotypes 9
Earliest

J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
Latest

J:267911 Timmermans S, et al., Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J. JCI Insight. 2018 Jul 12;3(13)

TSS for Acbd4:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr105303	Chr11:102992515-102992552 (+)	10 bp
Tssr105304	Chr11:102992561-102992575 (+)	44 bp
Tssr105305	Chr11:102993841-102993852 (+)	1,323 bp
Tssr105306	Chr11:102993877-102993941 (+)	1,385 bp
Tssr105307	Chr11:102995581-102995594 (+)	3,064 bp
Tssr105308	Chr11:102995597-102995617 (+)	3,083 bp
Tssr105309	Chr11:102995620-102995637 (+)	3,105 bp
Tssr3688	Chr11:102995642-102995652 (+)	3,123 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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