About   Help   FAQ
Ttc23 Gene Detail
Summary
  • Symbol
    Ttc23
  • Name
    tetratricopeptide repeat domain 23
  • Synonyms
    1600012K10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914259
    NCBI Gene: 67009
  • Alliance
    genome feature page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:67295180-67378370 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 37.06 cM, cytoband C
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2975 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914259
 protein coding gene Chr7:67295180-67412660 (+)
129S1/SvImJ ENSMUSG00200011032
 protein coding gene Chr7:54001904-54120100 (+)
A/J ENSMUSG00195012705
 protein coding gene Chr7:58426336-58544531 (+)
AKR/J ENSMUSG00220020227
 protein coding gene Chr7:51927183-52045394 (+)
BALB/cJ ENSMUSG00180004428
 protein coding gene Chr7:55136327-55254536 (+)
C3H/HeJ ENSMUSG00175010193
 protein coding gene Chr7:55928892-56047079 (+)
C57BL/6NJ ENSMUSG00215013251
 protein coding gene Chr7:55072143-55189717 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029851
 protein coding gene Chr7:70347629-70428899 (+)
CAST/EiJ ENSTCUG00005011987
 protein coding gene Chr7:58614264-58730201 (+)
CBA/J ENSMUSG00210019784
 protein coding gene Chr7:55767345-55885534 (+)
DBA/2J ENSMUSG00185006052
 protein coding gene Chr7:60110815-60228379 (+)
FVB/NJ ENSMUSG00205003974
 protein coding gene Chr7:55770870-55887164 (+)
JF1/MsJ ENSUMUG00000007780
 protein coding gene Chr7:64839487-64954620 (+)
LP/J ENSMUSG00230017391
 protein coding gene Chr7:66191864-66310109 (+)
NOD/ShiLtJ ENSMUSG00190006736
 protein coding gene Chr7:55875631-55993816 (+)
NZO/HlLtJ ENSMUSG00225015931
 protein coding gene Chr7:64467279-64585382 (+)
PWK/PhJ ENSLUMG00010018145
 protein coding gene Chr7:54395031-54512985 (+)
SPRET/EiJ ENSMSPG00010003017
 protein coding gene Chr7:54753502-54858314 (+)
WSB/EiJ ENSIUOG00005004471
 protein coding gene Chr7:56325848-56443984 (+)



Homology
more
  • Human Ortholog
    TTC23, tetratricopeptide repeat domain 23
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TTC23, tetratricopeptide repeat domain 23
  • Synonyms
    HCC-8
  • Links
    NCBI Gene ID: 64927
    UniProt: Q5W5X9

  • Chr Location
    15q26.3; chr15:99136323-99251226 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    57
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67009 NCBI Gene Model | MGI Sequence Detail 83191 C57BL/6J ±  kb
transcript NM_001168477 RefSeq | MGI Sequence Detail 3629 C57BL/6  
polypeptide Q8CHY7 UniProt | EBI | MGI Sequence Detail 488 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 58
    cDNA 58

    Microarray probesets 2
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 15
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:284228 Ikegami K, et al., Effect of expression alteration in flanking genes on phenotypes of St8sia2-deficient mice. Sci Rep. 2019 Sep 20;9(1):13634
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory